Evidence map›Paper›PMID 36789943›Full record

ArticleThe American journal of clinical nutrition2023

Diet quality and risk of gastric adenocarcinoma: The Multiethnic Cohort.

Nicholas Acuna, Song-Yi Park, Loïc Le Marchand, James R Hébert, Carol Boushey, Lynne R Wilkens, Anna H Wu, V Wendy Setiawan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Association between priori and posteriori dietary patterns and gastric cancer risk: an updated systematic review and meta-analysis of observational studies.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
    Pooled it
  3. Pooled it
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  7. Co-infection ofJournal of virology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nicholas AcunaDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Song-Yi ParkEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
Loïc Le MarchandEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
James R HébertDepartment of Epidemiology and Biostatistics and Cancer Prevention and Control Program, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Carol BousheyEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
Lynne R WilkensEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, HI, USA.
Anna H WuDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
V Wendy SetiawanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: vsetiawa@med.usc.edu.
University of Hawaiʻi at Mānoa · USUniversity of Southern California · USUniversity of South Carolina · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Dietary Quality Indexes and Cancer Risk: the Multiethnic Cohort StudyR03CA223890 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI PARK, SONG-YI · 2019 to 2020
$154k
NCI NIH HHS R03 CA223890NCI NIH HHS U01 CA164973NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

backgroundCertain dietary patterns (i.e., low intake of fruit/vegetables and high intake of salt and processed meats) have been associated with the risk of gastric cancer. However, it is unclear whether overall diet quality assessed by predefined indices that consider the complexity of dietary intake is associated with gastric cardia and distal adenocarcinoma.

objectivesTo examine the association of a variety of diet indices with the risk of gastric cardia and distal adenocarcinoma and assess whether there are any subgroups that may benefit from better diets to reduce the risk of gastric adenocarcinoma.

methodsDietary indices of interest included the Alternative Healthy Index (AHEI)-2010, Healthy Eating Index (HEI)-2015, the Dietary Approach to Stop Hypertension, alternate Mediterranean diet (aMED), and the energy-adjusted Dietary Inflammatory Index.

resultsAfter an average follow-up time of 19.2 years, there were 836 incident cases of gastric distal adenocarcinoma and 207 cases of gastric cardia adenocarcinoma. We did not observe any significant associations between the dietary indices and gastric cancer for either anatomic site. Among former aspirin users, we observed an inverse association between aMED with distal cancer (HR

conclusionsIn a multiethnic population, we did not observe overall significant associations between these dietary quality indices and risk of gastric cancer. However, among former aspirin users and never smokers, there could be a reduction of gastric distal adenocarcinoma risk with a higher adherence to a Mediterranean diet.

Indexed as

AdenocarcinomaDiet, MediterraneanStomach NeoplasmsAspirinCohort StudiesDietHumansRisk FactorsAspirincancer epidemiologycohortdiet qualitygastric cancernutrition

Identifiers

PMID36789943
PMCPMC10196603
OpenAlexW4312057455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.