Evidence map›Paper›PMID 36789835›Full record

ArticleJournal of the American Heart Association2023

High Burden of Premature Ventricular Complex Increases the Risk of New-Onset Atrial Fibrillation.

Po-Tseng Lee, Mu-Hsian Huang, Ting-Chung Huang, Chi-Hui Hsu, Sheng-Hsian Lin, Ping-Yen Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Electrocardiogram markers predicting ischemic stroke after acute coronary syndrome.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  6. Article
  7. Article
  8. Diagnostic reliability of monitoring for premature atrial and ventricular complexes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Po-Tseng LeeInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan.
Mu-Hsian HuangDivision of Cardiology, Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan.ORCID 0000-0003-4742-0056
Ting-Chung HuangInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan.ORCID 0000-0002-6397-0843
Chi-Hui HsuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan.ORCID 0000-0002-4095-3004
Sheng-Hsian LinInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan.ORCID 0000-0002-2925-5352
Ping-Yen LiuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan.ORCID 0000-0002-3643-5204
National Cheng Kung University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background High burden of premature ventricular complex (PVC) leads to increased cardiovascular mortality. A recent nationwide population-based study demonstrated that PVC is associated with an increased risk of atrial fibrillation (AF). However, the relationship between PVC burden and new-onset AF has not been investigated. The purpose of the study is to elucidate whether PVC burden is associated with new-onset AF. Methods and Results We designed a single-center, retrospective, large population-based cohort study to evaluate the role of PVC burden and new-onset AF in Taiwan. Patients who were AF naïve with PVC were divided into the low burden group (<1000/day) and moderate-to-high burden group (≥1000/day) based on the 24-h Holter ECG report. New-onset AF was defined as a new or first detectable event of either a persistent or paroxysmal AF. A total of 16 030 patients who were AF naïve and underwent 24-h Holter ECG monitoring were enrolled in this study, with a mean follow-up time of 973 days. A propensity score-matched analysis demonstrated that the moderate-to-high burden PVC group had a higher risk of developing new-onset AF than that of the low burden PVC group (4.91% versus 2.73%,

Indexed as

Atrial FibrillationVentricular Premature ComplexesCohort StudiesElectrocardiography, AmbulatoryHumansRetrospective Studies24‐h Holter ECGnew‐onset atrial fibrillationpremature ventricular complexpremature ventricular complex‐induced atrial fibrillation

Identifiers

PMID36789835
PMCPMC10111494
OpenAlexW4320857857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.