Evidence map›Paper›PMID 36789689›Full record

ArticleActa biochimica et biophysica Sinica2022

ZNF3 regulates proliferation, migration and invasion through MMP1 and TWIST in colorectal cancer.

Le Du, Ning Liu, Jianfeng Jin, Meng Cao, Yuantian Sun, Xinzheng Gao, Banzhan Ruan, Shangfeng Yang, Dongsheng Ge, Yingzhuan Ye and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Le DuHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Ning LiuDepartment of Gastrointestinal Surgery, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou 571199, China.
Jianfeng JinDepartment of Biochemistry and Molecular Biology, Hainan Medical University, Haikou 571199, China.
Meng CaoCollege of Biomedical Information and Engineering, Hainan Medical University, Haikou 571199, China.
Yuantian SunHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Xinzheng GaoHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Banzhan RuanHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Shangfeng YangHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Dongsheng GeDepartment of Gastrointestinal Surgery, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou 571199, China.
Yingzhuan YeHainan Provincial Key Laboratory of Carcinogenesis and Intervention; Department of Biology, Hainan Medical University, Haikou 571199, China.
Yinxi ZhouDepartment of Biochemistry and Molecular Biology, Hainan Medical University, Haikou 571199, China.
Erfei ChenKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.
Jin YangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.
Hainan Medical University · CNMinistry of Education of the People's Republic of China · CNNorthwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a malignant tumor with a high incidence and mortality worldwide. Currently, the underlying molecular mechanisms of CRC are still unclear. Zinc finger protein 3 (ZNF3) is a zinc-finger transcription factor that has been reported as a candidate for breast cancer prognosis, suggesting its involvement in the regulation of tumorigenesis. However, the association between ZNF3 and CRC remains unknown. To investigate the role of ZNF3 in CRC, we first analyze the correlation between ZNF3 expression and CRC, and the results demonstrate that ZNF3 is highly expressed in CRC tissue and cells, which is associated with the age of CRC patients.

Indexed as

Colorectal NeoplasmsMatrix Metalloproteinase 1Neoplasm InvasivenessTranscription FactorsCell Line, TumorCell MovementCell ProliferationCell Transformation, NeoplasticGene Expression Regulation, NeoplasticHumansNuclear ProteinsTwist-Related Protein 1Zinc FingersMatrix Metalloproteinase 1MMP1 protein, humanNuclear ProteinsTranscription FactorsTWIST1 protein, humanTwist-Related Protein 1colorectal cancerinvasionmigrationproliferationZNF3

Identifiers

PMID36789689
PMCPMC10157515
OpenAlexW4310713810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.