ArticleInternational journal of methods in psychiatric research2023
Differential symptom weighting in estimating empirical thresholds for underlying PTSD severity: Toward a "platinum" standard for diagnosis?
Article in International journal of methods in psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Beyond Jacobson and Truax: Estimation of Clinical Significance Trajectories in the Coping Power Intervention Using Measurement Error-Corrected Multilevel Modeling.Behavior therapy · 2025Trial
- Project Harmony 2.0: protocol for an updated and expanded individual patient data meta-analysis and virtual clinical trial of treatments for comorbid PTSD and substance use disorders.European journal of psychotraumatology · 2026Article
- Advancing PTSD-Substance Use Comorbidity Treatment Research Through Applying FAIR and FACT Data Science Frameworks inJournal of studies on alcohol and drugs · 2026Article
- Article
- A primer on intensive longitudinal psychometrics.Behavior research methods · 2026Review
- Being Mindful About Overuse of Total Scores: a Comparison of Total Scores and Moderated Nonlinear Factor Analysis Scores in Assessing Mindfulness Across Race/Ethnicity, Age, and PTSD Diagnosis.Prevention science : the official journal of the Society for Prevention Research · 2025Article
- Severe PTSD or just PTSD?European journal of psychotraumatology · 2025Article
- How changes in post-traumatic stress disorder (PTSD) severity mediate substance use disorder (SUD) severity during and after treatment for co-occurring PTSD and SUD: Results from Project Harmony.Addiction (Abingdon, England) · 2025Observational
- PACAP associated with precise PTSD and fear extinction response in women.Psychoneuroendocrinology · 2025Article
- Practical Implications of Sum Scores Being Psychometrics' Greatest Accomplishment.Psychometrika · 2024Article
- The Hidden Psychometric Model Underlying thePsychiatric services (Washington, D.C.) · 2024Article
- Differential symptom weighting in estimating empirical thresholds for underlying PTSD severity: Toward a "platinum" standard for diagnosis?International journal of methods in psychiatric research · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
objectiveSymptom counts as the basis for Post-Traumatic Stress Disorder (PTSD) diagnoses in the DSM presume each symptom is equally reflective of underlying disorder severity. However, the "equal weight" assumption fails to fit PTSD symptom data when tested. The present study developed an enhanced PTSD diagnosis based on (a) a conventional PTSD diagnosis from a clinical interview and (b) an empirical classification of full PTSD that reflected the relative clinical weights of each symptom.
methodBaseline structured interview data from Project Harmony (N = 2658) was used. An enhanced diagnosis for full PTSD was estimated using an empirical threshold from moderated nonlinear factor analysis (MNLFA) latent PTSD scale scores, in combination with a full conventional PTSD diagnosis based on interview data.
resultsOne in 4 patients in the sample had a PTSD diagnosis that was inconsistent with their empirical PTSD grouping, such that the enhanced diagnostic standard reduced the diagnostic discrepancy rate by 20%. Veterans, and in particular female Veterans, were at greatest odds for discrepancy between their underlying PTSD severity and DSM diagnosis.
conclusionPsychometric methodologies that differentially weight symptoms can complement DSM criteria and may serve as a platform for symptom prioritization for diagnoses in future editions of DSM.
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