Evidence map›Paper›PMID 36789532›Full record

ArticleBiology letters2023

Recovery of constitutive immune function after migratory endurance flight in free-living birds.

Cas Eikenaar, Alessia Ostolani, Sven Hessler, Ellen Y Ye, Arne Hegemann

Open access · bronzeAbstract read
In one paragraph

Article in Biology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Endocrine and molecular regulation of seasonal avian immune function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Cas EikenaarInstitute of Avian Research 'Vogelwarte Helgoland', 26386 Wilhelmshaven, Germany.ORCID 0000-0003-1049-8036
Alessia OstolaniDepartment of Biology, University of Pisa, 56126 Pisa, Italy.
Sven HesslerInstitute of Avian Research 'Vogelwarte Helgoland', 26386 Wilhelmshaven, Germany.
Ellen Y YeInstitute of Avian Research 'Vogelwarte Helgoland', 26386 Wilhelmshaven, Germany.
Arne HegemannDepartment of Biology, Lund University, SE-223 62 Lund, Sweden.ORCID 0000-0002-3309-9866
Institute of Avian Research · DELund University · SEUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strenuous physical activity can negatively affect constitutive innate immune function (CIF), the always present first line of defence against pathogens. CIF is non-specific, and thus vital when encountering novel pathogens. A lowered CIF likely increases the risk of infection and disease. Migratory birds engage in truly extreme physical activity during their endurance flights, however, little is known about how they deal with the negative impact this has on their immune function. By collecting both between- and within-individual data we show, for the first time, that free-flying migratory birds can recover several parameters of CIF during stopovers, which are stationary periods in between migratory flights. With this, we provide an important piece of the puzzle on how migrating birds cope with the physiological challenges they face on their biannual journeys. Furthermore, our study stresses the importance of migratory stopovers beyond fuel accumulation.

Indexed as

Animal MigrationFlight, AnimalAnimalsBirdsImmunityNutritional Statusagglutinationbacterial killingeco-immunologylysismigrationphysiological recovery

Identifiers

PMID36789532
PMCPMC9929496
OpenAlexW4320856727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.