Evidence map›Paper›PMID 36789267›Full record

ArticleComputational and structural biotechnology journal2023

Spatial patterns of the cap-binding complex eIF4F in human melanoma cells.

Xinpu Tang, Yi Pu, Haoning Peng, Kaixiu Li, Sara Faouzi, Tianjian Lu, Dan Pu, Michael Cerezo, Jianguo Xu, Lu Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Xinpu TangInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Yi PuInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Haoning PengInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Kaixiu LiInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Sara FaouziINSERM U981, Gustave Roussy Cancer Campus, Villejuif, France.
Tianjian LuInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Dan PuLung Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
Michael CerezoUniversité Côte d'Azur, Nice, France.
Jianguo XuDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China.
Lu LiLung Cancer Center, West China Hospital of Sichuan University, Chengdu, China.
Caroline RobertINSERM U981, Gustave Roussy Cancer Campus, Villejuif, France.
Shensi ShenInstitute of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Sichuan University · CNInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a central node of protein synthesis, the cap-binding complex, eukaryotic translation initiation factor 4 F (eIF4F), is involved in cell homeostasis, development and tumorigenesis. A large body of literature exists on the regulation and function of eIF4F in cancer cells, however the intracellular localization patterns of this complex are largely unknown. Since different subsets of mRNAs are translated in distinct subcellular compartments, understanding the distribution of translation initiation factors in the cell is of major interest. Here, we developed an

Identifiers

PMID36789267
PMCPMC9918392
OpenAlexW4318566921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.