Evidence map›Paper›PMID 36789235›Full record

ArticleJournal of experimental pharmacology2023

Phytochemical Screening and Antimicrobial Activity Evaluation of Selected Medicinal Plants in Ethiopia.

Sileshi Dubale, Dereje Kebebe, Ahmed Zeynudin, Negera Abdissa, Sultan Suleman

Abstract read
In one paragraph

Article in Journal of experimental pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Optimization, Preparation, and Cytotoxic Potential ofCurrent topics in medicinal chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sileshi DubaleSchool of Pharmacy and Laboratory of Drug Quality (JuLaDQ), Jimma University, Jimma, Oromia, Ethiopia.ORCID 0000-0001-7528-4579
Dereje KebebeSchool of Pharmacy and Laboratory of Drug Quality (JuLaDQ), Jimma University, Jimma, Oromia, Ethiopia.ORCID 0000-0002-6531-2748
Ahmed ZeynudinMedical Laboratory School, Jimma University, Jimma, Oromia, Ethiopia.ORCID 0000-0002-0552-1783
Negera AbdissaDepartment of Chemistry, Wallaga University, Nekemte, Oromia, Ethiopia.
Sultan SulemanSchool of Pharmacy and Laboratory of Drug Quality (JuLaDQ), Jimma University, Jimma, Oromia, Ethiopia.ORCID 0000-0003-3046-6760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The emergence and spread of resistant microbes continue to be a major public health concern. Effective treatment alternatives, particularly from traditionally used medicinal plants, are needed. Objective: The main objective of this study was to conduct phytochemical screening and antimicrobial activity evaluation of selected traditionally used medicinal plants in Ethiopia. Methods: The ethnomedicinal use value frequency index (FI) was used to select twelve medicinal plants. Phytochemical classes of compounds were screened using different standard methods. Anti-microbial activities of plant extracts were evaluated against Results: The phytochemical constituents identified were flavonoids, alkaloids, glycosides, phenols, saponins, steroids, and terpenoids, with flavonoids, alkaloids, and phenols being the most abundant. The crude extracts and chloroform fractions of the extracts showed an activity against the tested strains. The crude extract of Conclusion: The majority of evaluated medicinal plants demonstrated remarkable activity against tested microbial strains, which can be attributed to the presence of secondary metabolites of different classes of compounds. The finding provided scientific evidence for the use of these traditionally used medicinal plants.

Indexed as

antimicrobial activitymedicinal plantsminimum inhibitory concentrationphytochemical screeningtraditional medicine

Identifiers

PMID36789235
PMCPMC9922502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.