Evidence map›Paper›PMID 36789174›Full record

ArticleRespirology case reports2023

A case of prolonged COVID-19 treated with tixagevimab/cilgavimab.

Takahiro Shimizu, Hiroki Shirasaki, Kazuhiro Okafuji, Aiko Sawazaki, Tasuku Iwabuchi, Ryo Matubayashi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Takahiro ShimizuDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.ORCID https://orcid.org/0000-0001-6226-1087
Hiroki ShirasakiDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.
Kazuhiro OkafujiDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.
Aiko SawazakiDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.
Tasuku IwabuchiDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.
Ryo MatubayashiDepartment of Internal Medicine Fukui Prefecture Saiseikai Hospital Fukui-shi Japan.
Fukui-ken Saiseikai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old woman presented to our hospital with a fever and cough. The patient had a medical history of follicular lymphoma treated with obinutuzumab. She was infected with an omicron variant of coronavirus disease 2019 and developed viral pneumonia. Antibiotics, molnupiravir, sotrovimab, and prednisolone were administered but were ineffective. The patient's symptoms and pneumonia persisted. She could not produce antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) because she was administered obinutuzumab. Finally, when we administered 300 mg of tixagevimab and cilgavimab, pneumonia immediately improved. However, the infection was prolonged for more than 4 months. Patients treated with anti-CD20 monoclonal antibodies may have a prolonged SARS-CoV-2 infection. In such cases, tixagevimab/cilgavimab may be effective.

Indexed as

COVID‐19follicular lympomaObinutuzumabSARS‐Cov‐2tixagevimab/cilgavimab

Identifiers

PMID36789174
PMCPMC9912017
OpenAlexW4319984212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.