Evidence map›Paper›PMID 36788963›Full record

ReviewRevista panamericana de salud publica = Pan American journal of public health2023

Dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean: a systematic review.

Letícia L M Santos, Erika Carvalho de Aquino, Suleimy Marinho Fernandes, Yves Mauro F Ternes, Valéria C de R Feres

Abstract readReview
In one paragraph

Review in Revista panamericana de salud publica = Pan American journal of public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
  8. Article
  9. Chikungunya in a co-circulation setting: diagnostic discrepancies and clinical variation between RT-PCR-positive cases and notified data in Foz do Iguaçu, Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  10. Review
  11. Leveraging Climate Data Through Intelligent Systems for the Prediction of Arbovirus Transmission byInternational journal of environmental research and public health · 2025
    Article
  12. Larvicidal Activity ofThe Yale journal of biology and medicine · 2025
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Letícia L M SantosMolecular Biology Laboratory and Technologies Applied to Laboratory Diagnosis Faculty of Pharmacy Federal University of Goias Goiânia Brazil Molecular Biology Laboratory and Technologies Applied to Laboratory Diagnosis, Faculty of Pharmacy, Federal University of Goias, Goiânia, Brazil.
Erika Carvalho de AquinoPublic Health Department Institute of Tropical Pathology and Public Health Federal University of Goias Goiânia Brazil Public Health Department, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiânia, Brazil.
Suleimy Marinho FernandesLaboratory of Virology and Cell Culture Institute of Tropical Pathology and Public Health Federal University of Goias Goiânia Brazil Laboratory of Virology and Cell Culture, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiânia, Brazil.
Yves Mauro F TernesPublic Health Department Institute of Tropical Pathology and Public Health Federal University of Goias Goiânia Brazil Public Health Department, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiânia, Brazil.
Valéria C de R FeresMolecular Biology Laboratory and Technologies Applied to Laboratory Diagnosis Faculty of Pharmacy Federal University of Goias Goiânia Brazil Molecular Biology Laboratory and Technologies Applied to Laboratory Diagnosis, Faculty of Pharmacy, Federal University of Goias, Goiânia, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To characterize the distribution profile of dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean and to identify possible factors associated with the risk of dissemination and severity of these arboviruses. Methods: The protocol of this review was registered on the PROSPERO platform. Searches were carried out in the following databases: Virtual Health Library, MEDLINE/PubMed, and Embase. The search terms were: Zika virus, Zika virus infection, dengue, dengue virus, chikungunya virus, chikungunya fever, epidemiology, observational study, Latin America, and Caribbean region. Studies that addressed the distribution of these arboviruses and the risk factors associated with dengue, Zika virus disease, and chikungunya, published between January 2000 and August 2020 in English, Portuguese, and Spanish, were included. Results: Of 95 studies included, 70 identified risk factors, clinical manifestations, and outcomes for arbovirus infections and 25 described complications and/or deaths. The highest frequency of confirmed cases was for dengue. Brazil reported most cases of the three arboviruses in the period analyzed. Environmental and socioeconomic factors facilitated the proliferation and adaptation of vectors, and host-related factors were reported to aggravate dengue. Most deaths were due to chikungunya, Zika virus disease caused most neurological alterations, and dengue resulted in greater morbidity leading to more frequent hospitalization. Conclusions: The review provides a broad view of the three arboviruses and the intrinsic aspects of infections, and highlights the factors that influence the spread of these viruses in the populations studied.

Indexed as

Arbovirusesarbovirus infectionsCaribbeanLatin Americarisk factorssystematic review

Identifiers

PMID36788963
PMCPMC9910557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.