ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2023
Effects of β-alanine on intestinal development and immune performance of weaned piglets.
Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 31 citations in OpenAlex.
- Dietary anti- Escherichia coli K88 IgY enhances immune response and intestinal barrier function in piglets challenged with Escherichia coli K88.BMC veterinary research · 2026Article
- Effects of dietary SID Lys levels on growth performance, carcass traits, muscle composition, blood biochemistry, and colonic volatile fatty acids in growing Ningxiang pigs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- β-Alanine Is an Unexploited Neurotransmitter in the Pathogenesis and Treatment of Alzheimer's Disease.NeuroSci · 2026Review
- Gut microbiome-mediated transformation of dietary phytonutrients is associated with health outcomes.Nature microbiology · 2026Article
- Isatidis root polysaccharides ameliorates post-weaning diarrhea by promoting intestinal health and modulating the gut microbiota in piglets.The veterinary quarterly · 2025Article
- Antinociceptive Role of β-alanine in Hot Plate-induced Pain in Mice.Archives of Razi Institute · 2025Article
- Immunometabolism signature derived from on-treatment tumor specimens predicts immune checkpoint blockade response in metastatic melanoma.Discover oncology · 2025Article
- The potential mechanism of MicroRNA involvement in the regulation of muscle development in weaned piglets by tryptophan and its metabolites.BMC genomics · 2025Article
- Cinnamaldehyde Alleviates Salmonellosis in Chicks by Regulating Gut Health.Veterinary sciences · 2025Article
- Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics.BMC pregnancy and childbirth · 2025Article
- Impact of different feed intake levels on intestinal morphology and epithelial cell differentiation in piglets.Journal of animal science · 2025Article
- Safety and effects of scorpion-derived antimicrobial peptides as an alternative to antibiotic growth promoters in broilers: growth performance, immune function, and intestinal development.Frontiers in veterinary science · 2025Article
- Transcriptomics and Metabolomics Explain the Crisping Mechanisms of Broad Bean-Based Crisping Diets on Nile Tilapia (Metabolites · 2024Article
- Effects of monoglyceride blend on systemic and intestinal immune responses, and gut health of weaned pigs experimentally infected with a pathogenic Escherichia coli.Journal of animal science and biotechnology · 2024Article
- Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway.In vitro cellular & developmental biology. Animal · 2024Article
- Effect of β-Alanine Metabolite on Gut Integrity and Immunity in Commercial Broiler Chickens Infected withAnimals : an open access journal from MDPI · 2024Article
- Impact of dietary supplementation with β-alanine on the rumen microbial crude protein supply, nutrient digestibility and nitrogen retention in beef steers elucidated through sequencing the rumen bacterial community.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Article
- Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Effects of Tetrabasic Zinc Chloride on the Diarrhea Rate, Intestinal Morphology, Immune Indices and Microflora of Weaned Piglets.Animals : an open access journal from MDPI · 2024Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Beta-alanine is an important amino acid involved in several metabolic reactions in the body. The study aimed to investigate the effect of β-alanine supplementation on intestinal development and the immune performance of weaned piglets. Thirty-two 21-day-old healthy weaned piglets (half female and half male; Duroc × Landrace × Yorkshire) with an initial body weight of 8.11 ± 0.21 kg were randomly divided into 4 groups with 8 replicates of 1 pig each. The control group was fed a basal diet and the three experimental treatment groups were fed diets supplemented with 300, 600 and 1,200 mg/kg β-alanine, respectively. The trial lasted 28 days and the diets fed were divided into 2 phases: the late lactation period (day 1 to 14) and the nursery period (day 15 to 28), during which the weaned piglets had free access to food and water. The regulatory effects of β-alanine were further investigated in vitro using organoids obtained from the jejunum of piglets. In vivo, the addition of β-alanine to the diet had no significant effect on the growth performance of weaned piglets (
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