Evidence map›Paper›PMID 36788326›Full record

ArticleScientific reports2023

Standoff detection of bacterial spores by field deployable coherent Raman spectroscopy.

Nicola Coluccelli, Gianluca Galzerano, Paolo Laporta, Kelly Curtis, Claire L Lonsdale, Debbie Padgen, Christopher R Howle, Giulio Cerullo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nicola ColuccelliDipartimento di Fisica-Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133, Milan, Italy. nicola.coluccelli@polimi.it.
Gianluca GalzeranoIstituto di Fotonica e Nanotecnologie-CNR, Piazza Leonardo da Vinci 32, 20133, Milan, Italy.
Paolo LaportaDipartimento di Fisica-Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133, Milan, Italy.
Kelly CurtisDefence Science and Technology Laboratory, Porton Down, Salisbury, UK.
Claire L LonsdaleDefence Science and Technology Laboratory, Porton Down, Salisbury, UK.
Debbie PadgenDefence Science and Technology Laboratory, Porton Down, Salisbury, UK.
Christopher R HowleDefence Science and Technology Laboratory, Porton Down, Salisbury, UK.
Giulio CerulloDipartimento di Fisica-Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133, Milan, Italy.
Defence Science and Technology Laboratory · GBIstituto di Fotonica e Nanotecnologie · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibrational spectroscopies offer great potential for standoff detection of chemical and biological warfare agents, avoiding contamination to the operator and equipment. Among them, particularly promising is Coherent anti-Stokes Raman scattering (CARS) spectroscopy, using synchronized pump/Stokes laser pulses to set up a vibrational coherence of target molecules at a laser focus, which is read by further interaction with a probe pulse, resulting in the emission of a coherent beam detectable at a distance. CARS has previously demonstrated the capability to detect bacterial spores based on the Raman spectrum of the characteristic molecule calcium dipicolinate (CaDPA); however, a complex and bulky laser technology, which is only suitable for a laboratory environment, was employed. Here we develop a broadband CARS setup based on a compact, industrial grade ytterbium laser system. We demonstrate high signal-to-noise ratio detection of Bacillus atrophaeus spores at a concentration of 10

Indexed as

Spectrum Analysis, RamanSpores, BacterialLasersVibration

Identifiers

PMID36788326
PMCPMC9929236
OpenAlexW4320727057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.