ArticleScientific reports2023
Activity patterns are associated with fractional lifespan, memory, and gait speed in aged dogs.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Higher burden of neuropsychiatric symptom-like behaviors associated with canine cognitive dysfunction compared to normal aging in the Dog Aging Project.GeroScience · 2026Article
- Association of brachycephaly, sleep-disordered breathing, and inflammatory response in dogs.Journal of veterinary internal medicine · 2026Review
- Thoracic limb stride length is associated with cognitive impairment in aging dogs.Frontiers in veterinary science · 2026Article
- Hard-working or hardly working dogs stay young longer? Lifetime sports engagement, joint activity with the owner and breed type are associated with the severity of canine cognitive decline.Frontiers in veterinary science · 2026Article
- Physical Activity Monitors in Companion Animal Chronic Pain Research-A Review Focused on Osteoarthritis Pain.Animals : an open access journal from MDPI · 2025Review
- Estimated activity levels in dogs at population scale with linear and causal modeling.Frontiers in veterinary science · 2025Article
- Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.Frontiers in veterinary science · 2025Article
- Outcome assessment in veterinary pain studies: a pain in animals workshop (PAW) perspective.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- A randomized, controlled clinical trial demonstrates improved owner-assessed cognitive function in senior dogs receiving a senolytic and NAD+ precursor combination.Scientific reports · 2024Article
- Cross-sectional and longitudinal analysis of health-related quality of life (HRQoL) in senior and geriatric dogs.PloS one · 2024Article
- Development and validation of a sleep questionnaire, SNoRE 3.0, to evaluate sleep in companion dogs.Scientific reports · 2023Article
- The Relationship between Signs of Medical Conditions and Cognitive Decline in Senior Dogs.Animals : an open access journal from MDPI · 2023Article
- Where did my dog go? A pilot study exploring the movement ecology of farm dogs.Frontiers in veterinary science · 2023Article
- Sleep and cognition in aging dogs. A polysomnographic study.Frontiers in veterinary science · 2023Article
- Evaluation of risk factors for sleep-disordered breathing in dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maintaining an active lifestyle is considered a hallmark of successful aging. Physical activity significantly reduces the risk of cognitive decline and Alzheimer's disease in humans. However, pain and lack of motivation are important barriers to exercise. Dogs are a remarkable model for translational studies in aging and cognition as they are prone to Canine Cognitive Dysfunction syndrome, which has many similarities with Alzheimer's disease. According to owner reports, changes in activity levels are characteristic of this syndrome, with decreased daytime activity, but also excessive pacing, especially at sleep time. We used physical activity monitors to record the activity of 27 senior dogs and evaluated the association between activity level and age, fractional lifespan, cognitive status measured by an owner questionnaire and cognitive tests. We also assessed the relationship between activity and joint/spinal pain, and the off/on leash gait speed ratio (a potential marker of gait speed reserve and motivation). We found that activity patterns in dogs are associated with fractional lifespan and working memory. Additionally, dogs with higher on/off leash gait speed are more active in the afternoon of weekdays. These results encourage future studies evaluating how physical activity can improve or delay cognitive impairment in senior dogs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.