Evidence map›Paper›PMID 36788028›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Spared Premotor Areas Undergo Rapid Nonlinear Changes in Functional Organization Following a Focal Ischemic Infarct in Primary Motor Cortex of Squirrel Monkeys.

Erik J Plautz, Scott Barbay, Shawn B Frost, Ann M Stowe, Numa Dancause, Elena V Zoubina, Ines Eisner-Janowicz, David J Guggenmos, Randolph J Nudo

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Erik J PlautzDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160 rnudo@kumc.edu erik.plautz@utsouthwestern.edu.
Scott BarbayDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.ORCID 0000-0003-2470-7775
Shawn B FrostDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
Ann M StoweDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
Numa DancauseDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
Elena V ZoubinaDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
Ines Eisner-JanowiczDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
David J GuggenmosDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160.
Randolph J NudoDepartment of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160 rnudo@kumc.edu erik.plautz@utsouthwestern.edu.
University of Kansas Medical Center · US

Funding

Research Design and Analysis Core (RDAC)P30HD002528 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI DURHAM, DIANNE NONE · 1985 to 2015
$22.1M
REORGANIZATION OF MOTOR CORTEX FOLLOWING BRAIN INJURYR01NS030853 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NUDO, RANDOLPH J. · 1993 to 2020
$6.5M
Optimization of the Cortical Stimulation Protocol for Motor RecoveryU54NS048126 · NINDS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NUDO, RANDOLPH J. · 2005 to 2008
$3.8M
NICHD NIH HHS P30 HD002528NINDS NIH HHS R01 NS030853NINDS NIH HHS U54 NS048126
6 · The paper itself

Abstract

Recovery of motor function after stroke is accompanied by reorganization of movement representations in spared cortical motor regions. It is widely assumed that map reorganization parallels recovery, suggesting a causal relationship. We examined this assumption by measuring changes in motor representations in eight male and six female squirrel monkeys in the first few weeks after injury, a time when motor recovery is most rapid. Maps of movement representations were derived using intracortical microstimulation techniques in primary motor cortex (M1), ventral premotor cortex (PMv), and dorsal premotor cortex (PMd) in 14 adult squirrel monkeys before and after a focal infarct in the M1 distal forelimb area. Maps were derived at baseline and at either 2 (

Indexed as

Motor CortexStrokeAnimalsFemaleInfarctionMaleMovementSaimiricortical plasticityICMSmotor mapspremotor cortexrecovery of functionstroke

Identifiers

PMID36788028
PMCPMC10027035
OpenAlexW4320712706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.