Evidence map›Paper›PMID 36787363›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Design and synthesis of a small molecular NIR-II chemiluminescence probe for in vivo

Zhongxiang Chen, Lichao Su, Ying Wu, Jianyong Liu, Rongrong Wu, Qian Li, Chenlu Wang, Luntao Liu, Jibin Song

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
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  6. In Situ Synthesis of a Tumor Microenvironment-Activated Radiosensitizing CuAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Review
  8. Article
  9. Article
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  11. Review
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  15. Article
  16. Review
  17. Near-Infrared Afterglow ONOOACS applied materials & interfaces · 2023
    Article
  18. A FRET-Based Ratiometric HResearch (Washington, D.C.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhongxiang ChenMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Lichao SuMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.ORCID 0000-0001-9864-5904
Ying WuState key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 10010, China.
Jianyong LiuMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Rongrong WuMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Qian LiMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Chenlu WangMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Luntao LiuMinistry of Education (MOE) Key Laboratory for Analytical Science of Food Safety and Biology Institution, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Jibin SongState key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 10010, China.ORCID 0000-0003-4771-5006
Fuzhou University · CNBeijing University of Chemical Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemiluminescence (CL) with the elimination of excitation light and minimal autofluorescence interference has been wieldy applied in biosensing and bioimaging. However, the traditional emission of CL probes was mainly in the range of 400 to 650 nm, leading to undesired resolution and penetration in a biological object. Therefore, it was urgent to develop CL molecules in the near-infrared window [NIR, including NIR-I (650 to 900 nm) and near-infrared-II (900 to 1,700 nm)], coupled with unique advantages of long-time imaging, sensitive response, and high resolution at depths of millimeters. However, no NIR-II CL unimolecular probe has been reported until now. Herein, we developed an H

Indexed as

LuminescenceMolecular ProbesFluorescent DyesOptical ImagingSpectroscopy, Near-InfraredFluorescent DyesMolecular ProbesbioimagingchemiluminescenceH2Smetformin-induced hepatotoxicitysecond near-infrared window

Identifiers

PMID36787363
PMCPMC9974472
OpenAlexW4320710382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.