Evidence map›Paper›PMID 36787084›Full record

ArticleMolecular diversity2024

Design, synthesis and antifungal activity of novel amide derivatives containing a pyrrolidine moiety as potential succinate dehydrogenase inhibitors.

Xin Luo, Yifang Chen, Yu Wang, Zhifu Xing, Ju Peng, Jixiang Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. ChileanPlants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Control of Peach Brown Rot Disease Produced byJournal of fungi (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin LuoState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China.
Yifang ChenState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China.
Yu WangState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China.
Zhifu XingState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China.
Ju PengState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China.
Jixiang ChenState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry Education, Guizhou University, Huaxi District, Guiyang, 550025, China. 18230826028@163.com.ORCID http://orcid.org/0000-0001-8177-7476

Funding

the Cultivation Project of Guizhou University NO. (2020)06the Natural Science Foundation of Guizhou Province QKHJC-ZK[2022]039the Natural Science Foundation of Guizhou University NO. (2021)01
6 · The paper itself

Abstract

To discover new succinate dehydrogenase inhibitors (SDHI) fungicides, a series of amide derivatives containing a pyrrolidine moiety were designed and synthesized, and their antifungal activities were evaluated against Monilinia fructicola (M. fructicola), Rhizoctonia solani (R. solani), Fusarium graminearum schw (F. graminearum), Fusarium oxysporum (F. oxysporum), and Phytophthora infestans (P. infestans). Some compounds showed excellent antifungal activities against the five fungi. Among them, compound 6 showed broad-spectrum inhibitory activities. The EC

Indexed as

AmidesAntifungal AgentsDrug DesignPyrrolidinesSuccinate DehydrogenaseEnzyme InhibitorsMicrobial Sensitivity TestsPhytophthora infestansRhizoctoniaStructure-Activity RelationshipAmidesAntifungal AgentsEnzyme InhibitorspyrrolidinePyrrolidinesSuccinate DehydrogenaseAmide derivativesAntifungal activityCell membrane permeabilityPyrrolidineSDH inhibitor

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.