ArticleMolecular diversity2024
Cyrene: a very reactive bio-based chiral ketone in diastereoselective Passerini reactions.
Article in Molecular diversity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Turn-Induction in Peptides Incorporating Novel Cyrene-Derived α,α-Disubstituted Amino Acid.Journal of peptide science : an official publication of the European Peptide Society · 2026Article
- HPW-Catalyzed environmentally benign approach to imidazo[1,2-Beilstein journal of organic chemistry · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Cyrene, a green bioderived solvent from waste cellulose, was applied to the synthesis of novel α-acyloxyamide derivatives through a Passerini-3CR with carboxylic acids and isocyanides with good yields and diastereoselectivities under mild conditions. Cyrene showed exceptionally high reactivity and the degree of diastereoselection was dependent mostly on the isocyanide. DFT calculations as well as the experimental findings indicated that both kinetic and thermodynamic effects might explain the results.
Indexed as
Identifiers
36787083What OpenQuestion holds
Registered trials
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