Evidence map›Paper›PMID 36786997›Full record

ArticleDoklady. Biochemistry and biophysics2022

New Plant Species Showing Antiprotozoian Activity.

E G Cheremnykh, A V Osipov, V G Starkov, Nguyen Thi Thuy Trang, Nguyen Cuu Khoa, Hoang Ngoc Anh, Le Tien Dung, V I Tsetlin, Yu N Utkin

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Article in Doklady. Biochemistry and biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E G CheremnykhMental Health Research Centre, Moscow, Russia.
A V OsipovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
V G StarkovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Nguyen Thi Thuy TrangNguyen Tat Thanh University, Ho Chi Minh, Vietnam.
Nguyen Cuu KhoaInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh, Vietnam.
Hoang Ngoc AnhInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh, Vietnam.
Le Tien DungInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh, Vietnam.
V I TsetlinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Yu N UtkinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. utkin@ibch.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of extracts of ten plant species from Russia and five species from Vietnam on the growth and survival of ciliates Tetrahymena pyriformis were studied. T. pyriformis belongs to the subkingdom Protozoa, which also includes pathogens of protozoan infections. Extraction of dried plants was carried out with acidic and alkaline aqueous solutions, as well as with an aqueous ethanol. Various amounts of extracts were added to the ciliate cells, and the number of cells survived after incubation for 1 and 24 h was recorded. We found that our samples of several plants, including wormwood, harmala, and licorice, similarly to those studied earlier, exhibit antiprotozoal activity, which may indicate that the secondary metabolites are the same in plants from different regions. Using the ciliate T. pyriformis as a model organism, the presence of antiprotozoal activity in extracts of lilac, chondrilla, cinquefoil, hop, and elm was shown for the first time.

Indexed as

Antiprotozoal AgentsPlant ExtractsPlantsRussiaTetrahymena pyriformisAntiprotozoal AgentsPlant Extractsantiprotozoal activitychondrillacinquefoilelmhoplicoricelilacnettleTetrahymena pyriformiswormwood

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.