Evidence map›Paper›PMID 36786956›Full record

ArticleClinical oral investigations2023

Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO.

Daniela Adamo, Elena Calabria, Federica Canfora, Noemi Coppola, Stefania Leuci, Martina Mignogna, Lorenzo Lo Muzio, Francesca Spirito, Michele Giuliani, Lorenzo Azzi and 38 more

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors at 18 institutions in 1 country.

Daniela AdamoDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Elena CalabriaDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Federica CanforaDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy. federica.canfora@live.it.
Noemi CoppolaDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Stefania LeuciDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Martina MignognaDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Lorenzo Lo MuzioDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Francesca SpiritoDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Michele GiulianiDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Lorenzo AzziUnit of Oral Medicine and Pathology, ASST Dei Sette Laghi, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Marta DaniUnit of Oral Medicine and Pathology, ASST Dei Sette Laghi, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Giuseppe ColellaMultidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Chiara ColellaMultidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Lucio MontebugnoliDepartment of Biomedical and Neuromotor Sciences, Section of Oral Sciences, University of Bologna, Bologna, Italy.
Davide Bartolomeo GissiDepartment of Biomedical and Neuromotor Sciences, Section of Oral Sciences, University of Bologna, Bologna, Italy.
Mario GabrieleDepartment of Surgical Pathology, Medicine, Molecular and Critical Area, University of Pisa, Pisa, Italy.
Marco NisiDepartment of Surgical Pathology, Medicine, Molecular and Critical Area, University of Pisa, Pisa, Italy.
Andrea SardellaDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Giovanni LodiDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Elena Maria VaroniDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Amerigo GiudiceDepartment of Health Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Alessandro AntonelliDepartment of Health Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.
Alessio GambinoOral Medicine Section, Department of Surgical Science, CIR Dental School, University of Turin, Turin, Italy.
Giuliana AntonucciOral Medicine Section, Department of Surgical Science, CIR Dental School, University of Turin, Turin, Italy.
Paolo VescoviDepartment of Medicine and Surgery, Oral Medicine and Laser Surgery Unit, University Center of Dentistry, University of Parma, Parma, Italy.
Marco MeletiDepartment of Medicine and Surgery, Oral Medicine and Laser Surgery Unit, University Center of Dentistry, University of Parma, Parma, Italy.
Alessandra MajoranaDepartment of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Elena BardelliniDepartment of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Giuseppina CampisiDepartment of Surgical, Oncological, and Oral Sciences, University of Palermo, Palermo, Italy.
Vera PanzarellaDepartment of Surgical, Oncological, and Oral Sciences, University of Palermo, Palermo, Italy.
Francesco SpadariDepartment of Biomedical, Surgical and Dental Sciences, Maxillo-Facial and Dental Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Umberto GaragiolaDepartment of Biomedical, Surgical and Dental Sciences, Maxillo-Facial and Dental Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Monica PenteneroDepartment of Oncology, Oral Medicine and Oral Oncology Unit, University of Turin, Turin, Italy.
Samuele SuteraDepartment of Oncology, Oral Medicine and Oral Oncology Unit, University of Turin, Turin, Italy.
Matteo BiasottoDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Giulia OttavianiDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Margherita GobboDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Luca Guarda NardiniUnit of Oral and Maxillofacial Surgery, Ca' Foncello Hospital, Treviso, Italy.
Umberto RomeoDepartment of Oral Sciences and Maxillofacial Surgery, University of Rome La Sapienza, Rome, Italy.
Gianluca TenoreDepartment of Oral Sciences and Maxillofacial Surgery, University of Rome La Sapienza, Rome, Italy.
Rosario SerpicoMultidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Alberta LuccheseMultidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Carlo LajoloHead and Neck Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, School of Dentistry, Università Cattolica del Sacro Cuore, Rome, Italy.
Gioele GiocoHead and Neck Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, School of Dentistry, Università Cattolica del Sacro Cuore, Rome, Italy.
Massimo AriaDepartment of Economics and Statistics, University Federico II of Naples, Naples, Italy.
Luca D'AnielloDepartment of Social Sciences, University Federico II of Naples, Naples, Italy.
Michele Davide MignognaDepartment of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
SIPMO (Italian Society of Oral Pathology, Medicine)
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Milan · ITUniversity of Turin · ITUniversity of Foggia · ITUniversity of Trieste · ITMagna Graecia University · ITSapienza University of Rome · ITUniversity of Bologna · ITUniversity of Brescia · ITUniversity of Insubria · ITUniversity of Palermo · ITUniversity of Parma · ITUniversity of Pisa · ITCa' Foncello Hospital · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status.

methodsThree hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered.

resultsThe K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001

conclusionsThe prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood. CLINICAL RELEVANCE: Mood disorders and pain assessment should be carefully performed in relation to K-OLP to obtain a complete analysis of the patients.

Indexed as

DepressionLichen Planus, OralAnxietyFemaleHumansPainPrevalenceAnxietyDepressionKeratotic oral lichen planusMood disorderPain

Identifiers

PMID36786956
PMCPMC10264261
OpenAlexW4320709894

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