Evidence map›Paper›PMID 36786945›Full record

ArticleCellular and molecular neurobiology2023

Macrophage/Microglia Sirt3 Contributes to the Anti-inflammatory Effects of Resveratrol Against Experimental Intracerebral Hemorrhage in Mice.

Jidong Sun, Chen Pu, ErWan Yang, Hongchen Zhang, Yuan Feng, Peng Luo, Yuefan Yang, Lei Zhang, Xia Li, Xiaofan Jiang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jidong Sun *Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.ORCID http://orcid.org/0000-0003-0234-4686
Chen Pu *Department of Health Service, Fourth Military Medical University, Xi'an, China.
ErWan Yang *Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Hongchen ZhangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Yuan FengDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Peng LuoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Yuefan YangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Lei ZhangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Xia LiDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China.
Xiaofan Jiang *Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China. jiangxf@fmmu.edu.cn.
Shuhui Dai *Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 127 Changlexi Rd, Xi'an, China. daishneuo@fmmu.edu.cn.ORCID http://orcid.org/0000-0003-0779-2752
Xijing Hospital · CNAir Force Medical University · CN

Funding

National Natural Science Foundation of China 81901186National Natural Science Foundation of China 82101374National Natural Science Foundation of China 82171458
6 · The paper itself

Abstract

Intracerebral hemorrhage (ICH) is a devastating stroke type with high mortality and disability. Inflammatory response induced by macrophages/microglia (M/Ms) activation is one of the leading causes of brain damage after ICH. The anti-inflammatory effects of resveratrol (RSV) have already been evaluated in several models of central nervous system disease. Therefore, we designed the current study to assess the role of RSV in ICH and explore its downstream mechanism related to Sirt3. The autologous artery blood injection was administrated to create an ICH mouse model. M/Ms-specific Sirt3 knockout Sirt3

Indexed as

Brain InjuriesSirtuin 3AnimalsAnti-Inflammatory AgentsCerebral HemorrhageHematomaMacrophagesMiceMicrogliaResveratrolAnti-Inflammatory AgentsResveratrolSirt3 protein, mouseSirtuin 3Intracerebral hemorrhageMicrogliaNeuroinflammationResveratrolSirt3

Identifiers

PMID36786945
PMCPMC11410121
OpenAlexW4320709797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.