Evidence map›Paper›PMID 36786939›Full record

ArticleAIDS and behavior2023

Verbal Memory Performance and Depressive Symptoms in Persons with Treated HIV.

Lujie Xu, M John Gill, Christopher Power, Esther Fujiwara

Abstract read
PubMed Publisher
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lujie XuDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.ORCID http://orcid.org/0000-0003-1703-0313
M John GillDepartment of Medicine, University of Calgary, Calgary, AB, Canada.
Christopher PowerDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.
Esther FujiwaraDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada. efujiwara@ualberta.ca.

Funding

CIHR FRN 201803
6 · The paper itself

Abstract

The link between memory and comorbid depression in persons with HIV (PWH) is unclear based on evidence from published cohorts. We compared verbal memory in the HVLT-R in a well-characterized HIV cohort (n = 354) with (n = 102) or without (n = 252) comorbid depressive symptoms, and examined memory correlates in both scenarios. Memory fell within unimpaired ranges, but was lower in depressed than non-depressed PWH. Memory was related to quality of life, sociodemographic, and mental health factors, but not to assessed HIV-related or antiretroviral factors. However, longitudinally (n = 52) memory declined with presence and severity of depressive symptoms. In this treated cohort, verbal memory was unrelated to HIV-related variables but to quality of life and depressive symptoms. Greater performance decline over time also related to acute or ongoing depressive symptoms. These findings highlight the importance of addressing comorbid depressive symptoms to improve quality of life in persons with treated HIV.

Indexed as

DepressionHIV InfectionsVerbal LearningBayes TheoremFemaleHumansLongitudinal StudiesMaleMental HealthMiddle AgedQuality of LifeSociodemographic FactorsDepressionHIVHVLT-RMemory

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.