Evidence map›Paper›PMID 36786916›Full record

ArticleApplied microbiology and biotechnology2023

Utilization of delactosed whey permeate for the synthesis of ethyl acetate with Kluyveromyces marxianus.

Andreas Hoffmann, Alexander Franz, Thomas Walther, Christian Löser

Open access · hybridFull text read
In one paragraph

Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andreas HoffmannBioprocess Engineering, Institute of Natural Materials Technology, Technische Universität Dresden, 01062, Dresden, Germany.
Alexander FranzBioprocess Engineering, Institute of Natural Materials Technology, Technische Universität Dresden, 01062, Dresden, Germany.
Thomas WaltherBioprocess Engineering, Institute of Natural Materials Technology, Technische Universität Dresden, 01062, Dresden, Germany.
Christian LöserBioprocess Engineering, Institute of Natural Materials Technology, Technische Universität Dresden, 01062, Dresden, Germany. christian.loeser@tu-dresden.de.ORCID http://orcid.org/0000-0001-7890-3881
Technische Universität Dresden · DE

Funding

Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation und Technologie AiF 20311 BR
6 · The paper itself

Abstract

Ethyl acetate is an important organic solvent and currently produced from fossil carbon resources. Microbial synthesis of this ester from sugar-rich waste could be an interesting alternative. Therefore, synthesis of ethyl acetate by Kluyveromyces marxinanus DSM 5422 from delactosed whey permeate (DWP) was studied in an aerated stirred bioreactor at 40 °C. DWP is mainly composed of residual lactose and minerals. The minerals inhibited yeast growth, as witnessed by an increased lag period, a reduced growth rate, and an extended process duration. All experiments were therefore carried out with diluted DWP. In a series of batch experiments, the pH of iron-deficient DWP medium varied between 4.8 and 5.9. The pH of the cultivation medium significantly influenced cell growth and product syntheses, with the highest ethyl acetate yield of 0.347 g g

Indexed as

KluyveromycesWheyAcetatesFermentationIronLactoseWhey ProteinsAcetatesethyl acetateIronLactoseWhey ProteinsDelactosed whey permeateEthyl acetateFed-batch cultivationIron limitationRepeated-batch cultivation

Identifiers

PMID36786916
PMCPMC10006051
OpenAlexW4320709332

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read116
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.