Evidence map›Paper›PMID 36786860›Full record

Observational studyPediatric nephrology (Berlin, Germany)2023

Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia.

Jennifer A Rumpel, Beverly J Spray, Adam Frymoyer, Sydney Rogers, Seo-Ho Cho, Saritha Ranabothu, Richard Blaszak, Sherry E Courtney, Valerie Y Chock

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Observational
  5. A narrative review of the clinical applications of renal NIRS and integration with cerebral NIRS in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  6. Article
  7. Acute kidney injury in infants with hypoxic-ischemic encephalopathy.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jennifer A RumpelDivision of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Jarumpel@uams.edu.ORCID http://orcid.org/0000-0002-5883-218X
Beverly J SprayArkansas Children's Research Institute, Little Rock, AR, USA.
Adam FrymoyerDivision of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Sydney RogersDivision of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Seo-Ho ChoDivision of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Saritha RanabothuDivision of Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Richard BlaszakDivision of Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Sherry E CourtneyDivision of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Valerie Y ChockDivision of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
University of Arkansas for Medical Sciences · USStanford University · USArkansas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia are at high risk of acute kidney injury (AKI).

methodsWe performed a two-site prospective observational study from 2018 to 2019 to evaluate the utility of renal near-infrared spectroscopy (NIRS) in detecting AKI in 38 neonates with HIE receiving therapeutic hypothermia. AKI was defined by a delayed rate of serum creatinine decline (< 33% on day 3 of life, < 40% on day 5, and < 46% on day 7). Renal saturation (R

resultsAKI occurred in 20 of 38 neonates (53%). During the first 96 HOL, R

conclusionsLower RFTOE on renal NIRS and pH on infant first blood gas may be early predictors for AKI in neonates with HIE receiving therapeutic hypothermia. A higher resolution version of the Graphical abstract is available as Supplementary information.

Indexed as

Acute Kidney InjuryHypothermia, InducedHypoxia-Ischemia, BrainFemaleHumansInfantInfant, NewbornKidneyOximetryPregnancyAcute kidney injuryHypoxic ischemic encephalopathyNear-infrared spectroscopyNeonatesRenal fractional tissue oxygen extractionTherapeutic hypothermia

Identifiers

PMID36786860
OpenAlexW4320710055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.