Evidence map›Paper›PMID 36786845›Full record

ArticlePflugers Archiv : European journal of physiology2023

Aerobically trained older adults show impaired resting, but preserved exercise-induced circulating progenitor cell count, which was not improved by sprint interval training.

Zerbu Yasar, Mark D Ross, Christopher J Gaffney, Ruth D Postlethwaite, Russell Wilson, Lawrence D Hayes

Open access · hybridFull text read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Zerbu YasarActive Ageing Research Group, Institute of Health, University of Cumbria, Lancaster, UK.ORCID 0000-0001-8838-7286
Mark D RossSchool of Applied Sciences, Edinburgh Napier University, Edinburgh, UK.
Christopher J GaffneyLancaster Medical School, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.
Ruth D PostlethwaiteFaculty of Health and Life Sciences, Coventry University, Coventry, UK.
Russell WilsonSchool of Applied Sciences, Edinburgh Napier University, Edinburgh, UK.
Lawrence D HayesSport and Physical Activity Research Institute, School of Health and Life Sciences, University of the West of Scotland, Glasgow, UK. lawrence.hayes@uws.ac.uk.
Edinburgh Napier University · GBCoventry University · GBLancaster University · GBUniversity of Cumbria · GBUniversity of the West of Scotland · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older adults exhibit a reduced number and function of CD34 + circulating progenitor cells (CPC), a known risk factor for cardiovascular disease. Exercise promotes the mobilisation of CPCs from bone marrow, so whether ageing per se or physical inactivity in older age reduces CPCs is unknown. Thus, this study examined the effect of age on resting and exercise-induced changes in CPCs in aerobically trained adults and the effect of 8 weeks of sprint interval training (SIT) on resting and exercise-induced CPCs in older adults. Twelve young (22-34 years) and nine older (63-70 years) adults participated in the study. Blood was sampled pre and immediately post a graded exercise test to exhaustion in both groups. Older participants repeated the process after 8 weeks of SIT (3 × 20 s 'all-out' sprints, 2 × a week). Total CPCs (CD34

Indexed as

Endothelial Progenitor CellsHigh-Intensity Interval TrainingAgedAgingCell CountHumansStem CellsAgeingEndothelialEndothelial progenitor cellsHIITSprintVascular

Identifiers

PMID36786845
PMCPMC10011317
OpenAlexW4320709513

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read60
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.