Evidence map›Paper›PMID 36786615›Full record

ArticlemSphere2023

TgTKL4 Is a Novel Kinase That Plays an Important Role in

Hilary Montano, Ramu Anandkrishnan, Vern B Carruthers, Rajshekhar Y Gaji

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Animals : an open access journal from MDPI · 2025
    Article
  4. Article
  5. Article
  6. TKL family kinases in human apicomplexan pathogens.Molecular and biochemical parasitology · 2024
    Review
  7. Review
  8. Proteomics Applications inPathogens (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hilary MontanoDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Ramu AnandkrishnanDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Vern B CarruthersDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-6859-8895
Rajshekhar Y GajiDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.ORCID 0000-0002-9505-2123
Virginia–Maryland College of Veterinary Medicine · USUniversity of Michigan · US

Funding

Exploring the function of a novel tyrosine kinase like (TKL) protein in Toxoplasma endodyogenyR21AI162606 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GAJI, RAJSHEKHAR · 2022 to 2023
$440k
NIAID NIH HHS R21 AI162606
6 · The paper itself

Abstract

Protein kinases of the protozoan parasite Toxoplasma gondii have been shown to play key roles in regulating parasite motility, invasion, replication, egress and survival within the host. The tyrosine kinase-like (TKL) kinase family of proteins are a set of poorly studied kinases that our recent studies have indicated play a critical role in

Indexed as

ToxoplasmaToxoplasmosisAnimalsCell CycleMammalsMiceProteomeProtozoan ProteinsProteomeProtozoan Proteinsapicomplexan parasiteskinasesToxoplasma gondii

Identifiers

PMID36786615
PMCPMC10117109
OpenAlexW4320709596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.