Evidence map›Paper›PMID 36786559›Full record

ArticlemBio2023

Phospholipase B Is Critical for Cryptococcus neoformans Survival in the Central Nervous System.

Mohamed F Hamed, Glauber Ribeiro de Sousa Araújo, Melissa E Munzen, Marta Reguera-Gomez, Carly Epstein, Hiu Ham Lee, Susana Frases, Luis R Martinez

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

  1. Molecular types, clinical profile, and exploratory virulence-associated phenotypes of clinical Cryptococcus isolates from Amazonas, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  8. Review
  9. The Pain Is in the Brain With the Sugar-Coated Killer.The Journal of infectious diseases · 2025
    Review
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  11. Review
  12. Article
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  15. Review
  16. Magnolol Inhibits the Growth ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  17. Frontiers in immunology · 2025
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Mohamed F HamedDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Glauber Ribeiro de Sousa AraújoLaboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filhos, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Melissa E MunzenDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Marta Reguera-GomezDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Carly EpsteinDepartment of Biomedical Sciences, NYIT College of Osteopathic Medicine, Old Westbury, New York, USA.
Hiu Ham LeeDepartment of Biomedical Sciences, NYIT College of Osteopathic Medicine, Old Westbury, New York, USA.
Susana FrasesLaboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filhos, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Luis R MartinezDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0001-6372-6501
University of Florida · USNew York Institute of Technology · USUniversidade Federal do Rio de Janeiro · BRMansoura University · EG

Funding

Unraveling Cryptococcus neoformans mechanisms of brain invasion and colonizationR01AI145559 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI MARTINEZ, LUIS R · 2019 to 2023
$2.6M
Defining a Good Death for High-Risk Neonates in the NICUF31NR009460 · NINR · OHIO STATE UNIVERSITY · PI FORTNEY, CHRISTINE A · 2005 to 2009
$125k
NIAID NIH HHS R01 AI145559NINR NIH HHS F31 NR009460
6 · The paper itself

Abstract

Cryptococcus neoformans (

Indexed as

CryptococcosisCryptococcus neoformansDementiaHIV InfectionsMeningoencephalitisAnimalsCentral Nervous SystemLysophospholipaseMiceVirulence FactorsLysophospholipaseVirulence Factorscerebral cryptococcosisCryptococcus neoformansgliaGXMnitric oxidephospholipase

Identifiers

PMID36786559
PMCPMC10127605
OpenAlexW4320709144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.