ArticleAutism research : official journal of the International Society for Autism Research2023
Autism severity and its relationship to disability.
Article in Autism research : official journal of the International Society for Autism Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07427940 (Omic Profile in Autism Spectrum Disorder), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Omic Profile in Autism Spectrum Disorder: From Cellular Level Towards Future Treatments
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Studies assessing domains pertaining to structural language in autism vary in reporting practices and approaches to assessment: A systematic review.Autism : the international journal of research and practice · 2024Pooled it
- Assessment of the Efficacy of Quercetin in Adult Patients With Autism Spectrum Disorder: A Randomized, Triple-Blind, Placebo-Controlled Trial.Human psychopharmacology · 2026Trial
- Trial
- Burden of Co-occurring Conditions and Perinatal Predictors of Epilepsy in Autism Spectrum Disorder: A Cross-Sectional Study of 1015 Children From Northwestern Mexico.Journal of autism and developmental disorders · 2026Article
- Effects of Community-Based Acceptance and Commitment Therapy on Quality of Life and Mental Health Outcomes for Mothers of Children With Autism Spectrum Disorder: A Pilot RCT in China.Journal of autism and developmental disorders · 2026Article
- Effects of Using Prompts During Parent-Child Shared Reading on the Language Development of Mildly Autistic Children.Journal of autism and developmental disorders · 2026Article
- Event- and Time-Based Prospective Memory and Time Perception in Autistic Adults With and Without Intellectual Disabilities.Autism research : official journal of the International Society for Autism Research · 2026Article
- Developmental and Psychiatric Conditions Among 5-7 Year Old Children with Non-persistent and Persistent Autism.Journal of autism and developmental disorders · 2026Article
- Initial diagnosis patterns of coexisting mental health and neurodevelopmental conditions in autistic children and youth: Evidence from a nationally representative sample in Canada.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Offenders with Autism Spectrum Disorder: A Clinical Case Series and Diagnostic Considerations in Forensic Psychiatry.Psychology research and behavior management · 2026Article
- The quality of life of parents of children with disabilities in Saudi Arabia: a systematic review.Frontiers in pediatrics · 2026Review
- Novel therapeutics in autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Association between breastfeeding and autism spectrum condition in Saudi Arabia: a case-control study.International breastfeeding journal · 2025Article
- The Role of Capoeira in Improving Motor and Social Skills in Children with Autism.Children (Basel, Switzerland) · 2025Article
- Trajectories of autism symptom severity for boys and girls across childhood.Autism : the international journal of research and practice · 2025Article
- The Metabolic Signature of Autism Spectrum Disorders Using Dried Blood Spots at Birth.Psychiatry investigation · 2025Article
- The Impact of Co-Occurring Behavioral and Emotional Problems on the Quality of Life of Caregivers of Autistic Children: A Preliminary Study.Journal of clinical medicine · 2025Article
- Investigating the Impact of Embedded Learning Opportunities on the Engagement of Children With Autism and Intellectual Disability.Journal of applied research in intellectual disabilities : JARID · 2025Article
- Cognitive Brain Networks and Enlarged Perivascular Spaces: Implications for Symptom Severity and Support Needs in Children with Autism.Journal of clinical medicine · 2025Article
- A cross-sectional study of public knowledge and stigma towards autism spectrum disorder in Lebanon.Scientific reports · 2025Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Autism severity is currently defined and measured based exclusively on the severity levels of the two core symptom domains: social-communication and restricted or repetitive patterns of behaviors and interests. Autistic individuals, however, are often diagnosed with other medical, developmental, and psychological co-occurring conditions. These additional challenges such as intellectual disability, limited expressive and/or receptive language, and anxiety disorders, can have a tremendous impact on the day-to-day lives of autistic individuals, for both their adaptive functioning as well as their sense of wellbeing. Furthermore, the initial presentation of core symptoms and their likelihood of changing over time are influenced by the presence of such co-occurring conditions. In order to truly understand how a person's autism impacts their life, both core symptoms as well as other challenges should be considered. This approach was recently taken byThe Lancet Commission on the future of care and clinical research in autism, which proposed the term "profound autism" for a subgroup of individuals presenting with high core symptom severity, co-occurring intellectual disability, and little or no language, who require extensive long-term care. Considering other individual factors such as daily living skills, specific support needs and environmental resources would also enhance the evaluation of disability in autistic individuals. As currently employed in the assessment of intellectual disability, a multidimensional approach to autism could provide a more comprehensive system for classification of impairment. At present, however, there is no formal way to designate the combined effect of these different aspects of autism on a person's life. A comprehensive outlook that acknowledges impairments, capabilities, co-occurring conditions, and environmental factors would be useful for identifying subgroups of individuals as well as for determining individual needs and strengths in clinical assessments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.