Evidence map›Paper›PMID 36785953›Full record

Observational studyHuman vaccines & immunotherapeutics2023

Efficacy of vaccination against the SARS-CoV-2 virus in patients with chronic kidney disease on hemodialysis.

María E Sanhueza, Pamela San Martín, Loreto Brantes, Sylvia Caro, Guillermo Carrasco, Eduardo Machuca

Abstract readObservational Study
In one paragraph

Observational study in Human vaccines & immunotherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María E SanhuezaNational Medical Directorate, NephroCare-Chile,Santiago, Chile.ORCID 0000-0001-7161-6935
Pamela San MartínNational Medical Directorate, NephroCare-Chile,Santiago, Chile.ORCID 0000-0003-1974-3050
Loreto BrantesNational Medical Directorate, NephroCare-Chile,Santiago, Chile.
Sylvia CaroNational Medical Directorate, NephroCare-Chile,Santiago, Chile.
Guillermo CarrascoNational Medical Directorate, NephroCare-Chile,Santiago, Chile.
Eduardo MachucaNational Medical Directorate, NephroCare-Chile,Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 has had a great impact on world health, patients on hemodialysis have a higher rate of infection and death due to COVID-19. Vaccination is important to control infection and improve the prognosis of infected patients. To describe the efficacy of vaccination against SARS-CoV-2 in Chilean patients on hemodialysis during the year 2021. Retrospective observational study. A total of 9,712 clinical records were reviewed. Data were presented as summary measures. Fisher's exact test, Mann-Whitney U test, and multivariate logistic regression were used for the analysis. Risk and survival analysis were calculated, considering a statistical significance of less than 0.05. The average age of the patients attended was 61.5 ± 14.6 years. Average time on dialysis 67.6 months and 35.0% diabetic. 93.2% of patients were vaccinated against SARS-CoV-2, 70.7% of them received booster doses. The risk of infection was higher for those who received one or no dose, compared to those who received booster doses against SARS-CoV-2: OR = 252.46 [165.13; 401.57]. Of the infected patients, 15.7% died from COVID-19. The risk of death was higher in unvaccinated or single-dose patients compared to those vaccinated with two doses: OR = 2.64 [2.23; 3.12]. Patients with two doses and a booster had a longer survival compared to those who received one or no dose of vaccination against SARS-CoV-2 (

Indexed as

COVID-19Renal Insufficiency, ChronicAgedHumansMiddle AgedRenal DialysisSARS-CoV-2VaccinationCoronavirusCOVID-19 vaccinesefficacyhemodialysisSARS-CoV-2

Identifiers

PMID36785953
PMCPMC10012891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.