Evidence map›Paper›PMID 36785872›Full record

ArticleJournal of the International AIDS Society2023

Alcohol use, suicidality and virologic non-suppression among young adults with perinatally acquired HIV in Thailand: a cross-sectional study.

Linda Aurpibul, Pope Kosalaraksa, Surinda Kawichai, Pagakrong Lumbiganon, Pradthana Ounchanum, Wipaporn Natalie Songtaweesin, Tavitiya Sudjaritruk, Kulkanya Chokephaibulkit, Supattra Rungmaitree, Tulathip Suwanlerk and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Linda AurpibulResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.ORCID 0000-0003-0246-8187
Pope KosalaraksaDepartment of Pediatrics, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kean, Thailand.
Surinda KawichaiDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Pagakrong LumbiganonDepartment of Pediatrics, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kean, Thailand.
Pradthana OunchanumDepartment of Pediatrics, Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand.
Wipaporn Natalie SongtaweesinDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0000-0003-3440-732X
Tavitiya SudjaritrukDepartment of Pediatrics and Clinical and Molecular Epidemiology of Emerging and Re-emerging Infectious Diseases Research Cluster, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID 0000-0002-3686-4623
Kulkanya ChokephaibulkitDepartment of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-0140-4600
Supattra RungmaitreeDepartment of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Tulathip SuwanlerkTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
Jeremy L RossTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.
Annette H SohnTREAT Asia/amfAR - The Foundation for AIDS Research, Bangkok, Thailand.ORCID 0000-0002-0209-3285
Thanyawee PuthanakitDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0000-0002-0019-2183
Thai PAPAYA study team
Chulalongkorn University · THChiang Mai University · THKhon Kaen University · THSiriraj Hospital · THChiangRai Prachanukroh Hospital · TH

Funding

The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
NCI NIH HHSNHLBI NIH HHSNIAAA NIH HHSNIAID NIH HHS U01 AI069907NIDA NIH HHSNIDDK NIH HHSNIH HHS U01AI069907NIMH NIH HHS
6 · The paper itself

Abstract

introductionYoung adults with perinatally acquired HIV (YA-PHIV) are facing transitions to adult life. This study assessed health risk behaviours (including substance use), mental health, quality of life (QOL) and HIV treatment outcomes of Thai YA-PHIV.

methodsA cross-sectional study was conducted in Thai YA-PHIV aged 18-25 years who were enrolled in a prospective cohort study at five tertiary paediatric HIV care centres in Thailand. Study data were obtained through face-to-face interviews from November 2020 to July 2021. Assessments were performed for alcohol use (Alcohol Use Disorders Identification Test; AUDIT), smoking (Fagerstrom Test for Nicotine Dependence), drug/substance use (Drug Abuse Screening Test; DAST-10), depression (Patient Health Questionnaire for Adolescents; PHQ-A), anxiety (Generalized Anxiety Disorder; GAD-7) and QOL (World Health Organization QOL Brief-Thai). HIV treatment outcomes were extracted from the National AIDS Program database.

resultsOf 355 YA-PHIV, 163 (46%) were males: their median age was 21.7 (interquartile range, IQR 20.2-23.5) years. There were 203 YA-PHIV (58%) who reported ever having sex; 141 (40%) were sexually active in the past 6 months, of whom 86 (61%) reported 100% condom use. Overall, 49 (14%) met the criteria for harmful alcohol use; 28 (7.9%) were alcohol dependent. Sixty (17%) were current smokers and 37 (11%) used drugs/substances. The frequency of moderate up to severe symptoms for depression was 18% and for anxiety was 9.7%. Their overall QOL was good in 180 (51%), moderate in 168 (47%) and poor in five (1.4%). There were 49 YA-PHIV (14%) with CD4 <200 cells/mm

conclusionsRegular screening for alcohol use and mental health, including suicidality, would be useful to identify YA-PHIV who need more intensive psychosocial support or referral services to ensure they can achieve and maintain a high QOL into adult life.

Indexed as

AlcoholismHIV InfectionsSubstance-Related DisordersSuicideAdolescentAdultChildCross-Sectional StudiesFemaleHumansInfectious Disease Transmission, VerticalMaleProspective StudiesQuality of LifeSuicidal IdeationThailandalcoholAsiaperinatal HIV infectionsuicidalityvirologic non-suppressionyoung adults

Identifiers

PMID36785872
PMCPMC9925945
OpenAlexW4320710443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.