Evidence map›Paper›PMID 36785643›Full record

ArticleEuropean journal of radiology open2023

Current and upcoming radionuclide therapies in the direction of precision oncology: A narrative review.

Hina J Shah, Evan Ruppell, Rozan Bokhari, Parag Aland, Vikram R Lele, Connie Ge, Lacey J McIntosh

Abstract read
In one paragraph

Article in European journal of radiology open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Editorial: Women in radionuclide therapy: 2023.Frontiers in nuclear medicine · 2024
    Article
  10. Review
  11. Article
  12. What's new in cancer and molecular imaging.European journal of radiology open · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hina J ShahDepartment of Radiology, Division of Nuclear Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Evan RuppellDepartment of Radiology, University of Massachusetts Chan Medical School, Memorial Health Care, Worcester, MA 01655, USA.
Rozan BokhariDepartment of Radiology, Beth Israel Lahey Health, Burlington, MA 01803, USA.
Parag AlandIn-charge Nuclear Medicine and PET/CT, Infinity Medical Centre, Mumbai, Maharashtra 400015, India.
Vikram R LeleChief, Department of Nuclear Medicine and PET/CT, Jaslok Hospital and Research Centre, Mumbai, Maharashtra 400026, India.
Connie GeUniversity of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
Lacey J McIntoshDivision of Oncologic and Molecular Imaging, University of Massachusetts Chan Medical School / Memorial Health Care, Worcester, MA 0165, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As new molecular tracers are identified to target specific receptors, tissue, and tumor types, opportunities arise for the development of both diagnostic tracers and their therapeutic counterparts, termed "theranostics." While diagnostic tracers utilize positron emitters or gamma-emitting radionuclides, their theranostic counterparts are typically bound to beta and alpha emitters, which can deliver specific and localized radiation to targets with minimal collateral damage to uninvolved surrounding structures. This is an exciting time in molecular imaging and therapy and a step towards personalized and precise medicine in which patients who were either without treatment options or not candidates for other therapies now have expanded options, with tangible data showing improved outcomes. This manuscript explores the current state of theranostics, providing background, treatment specifics, and toxicities, and discusses future potential trends.

Indexed as

Cancer imagingNuclear medicineTheranostics

Identifiers

PMID36785643
PMCPMC9918751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.