Evidence map›Paper›PMID 36785578›Full record

ArticleJournal of multidisciplinary healthcare2023

Covid-19 Vaccine Side Effects and Its Associated Factors Among Healthcare Workers at Dessie Hospital, Ethiopia.

Reta Dewau, Elsabeth Addisu, Tilahun Dessie, Tesfaye Birhane, Sisay Eshete Tadesse, Amare Muche, Yitbarek Wasihun Feleke, Baye Akele, Melaku Yalew, Kemal Ahmed Seid and 11 more

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Reta DewauDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-6531-2468
Elsabeth AddisuDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-7389-3415
Tilahun DessieDepartment of Paediatrics, School of Medicine, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-9857-4077
Tesfaye BirhaneDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Sisay Eshete TadesseDepartment of Public Health Nutrition, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0003-2539-3755
Amare MucheDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-8533-3570
Yitbarek Wasihun FelekeDepartment of Health Education, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Baye AkeleDepartment of Clinical Laboratory, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Melaku YalewDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-7314-2523
Kemal Ahmed SeidDepartment of Infectious Disease, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0003-0525-3042
Yitayish DamtieDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-6783-6097
Bereket KefaleDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0003-1795-9886
Zinet Abegaz AsfawDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-2542-7671
Bezawit AdaneDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-0440-8826
Wondwosen MebratuDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-6262-7165
Ayechew AdemasDepartment of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0003-2602-162X
Niguss CherieDepartment of Reproductive health, School of Public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-3497-2663
Assefa AndargieDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-8409-7545
Muluken Genetu ChanieDepartment of Health Service Management, School of public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-7059-1449
Asnakew MollaDepartment of Health Service Management, School of public health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-7573-1594
Metadel AdaneDepartment of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0002-7039-4768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vaccines are a powerful choice to stop disease outbreaks, including covid-19. However, people are hesitant to take vaccinations due to uncertainty about side effects. So, this study aimed to assess covid-19 vaccine side-effect and its associated factors among healthcare workers in Dessie comprehensive specialized hospital, in Ethiopia. Methods: An institution-based cross-sectional study was conducted at Dessie Comprehensive and Specialized Hospital among 351 vaccinated healthcare workers from April 25 to May 25, 2021. Self-administrated questionnaires were used by consented health workers. Variance inflation factor (VIF) was used to assess the multicollinearity of independent variables. Bivariable and multivariable binary logistic regression were used to identify significant factors of vaccine side effects. The adjusted odds ratio (AOR) with a 95% confidence interval (CI) was reported as the effect size. Statistical significance was considered at p-value <0.05. Results: Overall, of vaccinated healthcare workers, 56.98% (95% CI, 50.86-61.26%) experienced at least one side effect. The majority of the side effects were fever (44.44%), headache (39.03%), fatigue (27.35%), injection site pain (25.93%), and nausea (24.22%). Healthcare workers with (≥10 years) of work experience (AOR: 3.74, 95% CI, 1.32-10.59), Hesitancy to take the first dose of the Covid-19 vaccine (AOR: 3.01, 95% CI, 1.82-4.99), underlying chronic disease (AOR: 14.41, 95% CI, (5.07-40.92)), being on antihypertensive medication (AOR: 0.15; 95% CI (0.02-0.93)), and unsafe perception of vaccine safety (AOR:3.50; 95% CI, 1.43-8.57) were independent factors of Covax vaccine side effect development. Conclusion: Overall, common vaccine side effects were identified in healthcare workers who have taken the Covax vaccine. Healthcare workers with (≥10 years) of work experience, Hesitancy to take the first dose, unsafe perception of vaccine safety, and underlined chronic disease were predictors of vaccine side effect occurrence. So, providing vaccine-related information to the community to be vaccinated is mandatory to reduce hesitancy and flaws regarding vaccine safety.

Indexed as

associated factorsCovid-19Ethiopiahealth care workersvaccine side effects

Identifiers

PMID36785578
PMCPMC9921431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.