Observational studyBiology of sex differences2023
Sex differences in subjective cognitive impairment and clinical correlates in Chinese patients with subthreshold depression.
Observational study in Biology of sex differences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- The effect of alexithymia on depression: evidence from meta-analysis.Frontiers in psychology · 2025Pooled it
- Sex differences in subjective cognitive impairment among Chinese patients with depression: A large-scale cross-sectional study.General psychiatry · 2026Article
- Subjective Cognitive Complaints and Symptom Severity in Patients With Borderline Personality Disorder.Actas espanolas de psiquiatria · 2025Article
- Exploring the neural mechanisms of electroacupuncture for cognitive impairment in depression using functional near-infrared spectroscopy: a randomized controlled trial.Frontiers in psychiatry · 2025Article
- Additive effect of admission hyperglycemia on left ventricular stiffness in patients following acute myocardial infarction verified by CMR tissue tracking.Cardiovascular diabetology · 2024Article
- Mental Fatigue Is Associated with Subjective Cognitive Decline among Older Adults.Brain sciences · 2023Article
- Bright light therapy-induced improvements of mood, cognitive functions and cerebellar functional connectivity in subthreshold depression: A randomized controlled trial.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveSubthreshold depression (SD) is a global mental health problem given its high prevalence, comorbidity, functional impairment, and its association with increased service utilization. However, currently little is known about sex differences of SD in cognitive impairment with clinical correlates. This study aims to explore sex differences in subjective cognitive impairment and clinically associated risk factors in Chinese patients with subthreshold depression (SD).
methodsA total of 126 patients with SD, 40 males and 86 females, aged 18-45 years, were included in this cross-sectional observational study. Their general information, psychological assessments, and psychiatric symptom assessments were collected online. The Patient Health Questionnaire depression-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Perceived Deficits Questionnaire-Depression (PDQ-D), and Toronto Alexithymia Scale (TAS-20) with 3 subdomains were used. The obtained scores were analyzed with partial correlation and multiple linear regression analysis models.
resultsOur results showed that females had significantly higher PDQ-D-20 total score than males. However, the differences in TAS-20 and subdomain score according to sex were not significant. Notably, TAS-20 and DDF (difficulty describing feelings) subdomain contributed to cognitive impairment in males, whereas both PHQ-9 total score and TAS-20 or DDF subdomain contributed to cognitive impairment in females.
conclusionThese findings revealed significant sex differences in cognitive impairment and clinical correlates in SD, which should be further followed-up in the future.
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