Evidence map›Paper›PMID 36782292›Full record

ArticlePorcine health management2023

Effects of β-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations.

Shawn M D Bearson, Julian M Trachsel, Bradley L Bearson, Crystal L Loving, Brian J Kerr, Daniel C Shippy, Tadele G Kiros

Open access · goldAbstract read
In one paragraph

Article in Porcine health management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shawn M D BearsonFood Safety and Enteric Pathogens Research Unit, USDA, ARS, National Animal Disease Center, 1920 Dayton Ave, Room 1403, Ames, IA, 50010, USA. shawn.bearson@usda.gov.
Julian M TrachselFood Safety and Enteric Pathogens Research Unit, USDA, ARS, National Animal Disease Center, 1920 Dayton Ave, Room 1403, Ames, IA, 50010, USA.
Bradley L BearsonAgroecosystems Management Research Unit, USDA, ARS, National Laboratory for Agriculture and the Environment, Ames, IA, USA.
Crystal L LovingFood Safety and Enteric Pathogens Research Unit, USDA, ARS, National Animal Disease Center, 1920 Dayton Ave, Room 1403, Ames, IA, 50010, USA.
Brian J KerrAgroecosystems Management Research Unit, USDA, ARS, National Laboratory for Agriculture and the Environment, Ames, IA, USA.
Daniel C ShippyFood Safety and Enteric Pathogens Research Unit, USDA, ARS, National Animal Disease Center, 1920 Dayton Ave, Room 1403, Ames, IA, 50010, USA.
Tadele G KirosPhileo by Lesaffre, North America, Milwaukee, WI, USA.
National Animal Disease Center · USNational Laboratory for Agriculture and the Environment · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe 2017 Veterinary Feed Directive eliminated the use of medically important antibiotics for growth promotion of food animals; thus, alternative growth promoters are highly desirable by food animal producers to enhance animal health and reduce pathogen colonization, including the human foodborne pathogen Salmonella. β(1-3)(1-6)-D-glucan (β-glucan) is a soluble fiber with prebiotic characteristics; it has been shown to modulate immune and intestinal functions that strengthen swine resistance to health challenges such as bacterial infections when supplemented in the diets of growing pigs. The current study evaluated the effects of a β-glucan product on gut microbial community structure as well as Salmonella shedding and intestinal colonization.

resultsFive-week-old pigs were fed a β-glucan amended diet at 500 g/ton (n = 13) or a non-amended control diet (n = 14) for three weeks, followed by inoculation of the 27 pigs with 1 × 10

conclusionAdministration of β-glucan altered the swine gut microbiome and reduced Salmonella colonization in the cecal contents.

Indexed as

Antibiotic alternativeMicrobiotaSalmonellaSwineβ-Glucan

Identifiers

PMID36782292
PMCPMC9926856
OpenAlexW4320481334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.