Evidence map›Paper›PMID 36782227›Full record

Trial reportBMC medicine2023

Postoperative Supplemental Oxygen in Liver Transplantation (PSOLT) does not reduce the rate of infections: results of a randomized controlled trial.

Wojciech Figiel, Grzegorz Niewiński, Michał Grąt, Marek Krawczyk, Jan Stypułkowski, Zbigniew Lewandowski, Maciej Krasnodębski, Waldemar Patkowski, Krzysztof Zieniewicz

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02857855 (The Impact of Postoperative Oxygen Therapy on the Results of Liver Transplantation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02857855 naunknown statusnot on this map

The Impact of Postoperative Oxygen Therapy on the Results of Liver Transplantation

TypeinterventionalSponsorMedical University of WarsawRan2016 to 2025Enrolled193ConditionsInfectionArms80% fraction of inspired oxygen for 6 postoperative hours, 28% fraction of inspired oxygen for 6 postoperative hours
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wojciech FigielDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Grzegorz NiewińskiDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Michał GrątDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland. michal.grat@gmail.com.ORCID 0000-0003-3372-3072
Marek KrawczykDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Jan StypułkowskiDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Zbigniew LewandowskiDepartment of Epidemiology and Biostatistics, Medical University of Warsaw, Oczki 3, 02-007, Warsaw, Poland.
Maciej KrasnodębskiDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Waldemar PatkowskiDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Krzysztof ZieniewiczDepartment of General, Transplant and Liver Surgery, Medical University of Warsaw, Banacha 1A, 02-097, Warsaw, Poland.
Medical University of Warsaw · PL

Funding

Narodowe Centrum Nauki 2019/34/E/NZ5/00433
6 · The paper itself

Abstract

backgroundDespite inconsistent evidence, international guidelines underline the importance of perioperative hyperoxygenation in prevention of postoperative infections. Further, data on safety and efficacy of this method in liver transplant setting are lacking. The aim was to evaluate efficacy and safety of postoperative hyperoxygenation in prophylaxis of infections after liver transplantation.

methodsIn this randomized controlled trial, patients undergoing liver transplantation were randomly assigned to either 28% or 80% fraction of inspired oxygen (FiO

resultsA total of 193 patients were included and randomized to 28% (n = 99) and 80% (n = 94) FiO

conclusionsPostoperative hyperoxygenation should not be used for prophylaxis of infections after liver transplantation due to the lack of efficacy.

trial registrationClinicalTrials.gov NCT02857855. Registered 7 July 2016.

Indexed as

Liver TransplantationBilirubinHumansIntensive Care UnitsOxygenPostoperative ComplicationsBilirubinOxygenInfectionIschemia-reperfusion injuryLiver transplantationMorbidityMortalityOxygen

Identifiers

PMID36782227
PMCPMC9924861
OpenAlexW4320482092

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.