Evidence map›Paper›PMID 36782218›Full record

ReviewPediatric rheumatology online journal2023

IgG4 related pericardium and lung disease in pediatric patient complicated with fatal massive hemoptysis: a case report and review of literature.

Moustafa Ali Saad, Hamdy Ahmed, Rasmia Elgohary, Hala Ibrahem El Gendy

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Pediatric rheumatology online journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Moustafa Ali SaadRheumatology and Clinical Immunology Unit, Internal Medicine Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt. moustafa.ali.saad@kasralainy.edu.eg.ORCID http://orcid.org/0000-0001-6070-9407
Hamdy AhmedDivision of Rheumatology, Department of Medicine, University of South Alabama, Mobile, AL, USA.ORCID http://orcid.org/0000-0002-7097-7314
Rasmia ElgoharyRheumatology and Clinical Immunology Unit, Internal Medicine Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-4002-1485
Hala Ibrahem El GendyRheumatology and Clinical Immunology Unit, Internal Medicine Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.
Cairo University · EGUniversity of South Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIgG4-related disease (IgG4-RD) is a progressive and sometimes fatal disease that rarely affects pediatric age group. It may affect the orbits, lacrimal and salivary glands, pancreas, kidneys, peritoneum and other organs. Lung and pleura are not commonly reported in IgG4-RD. We here present a rare case of pediatric IgG4-RD with rare involvement of pericardium, pleura and lungs. CASE PRESENTATION: A 13-year-old girl presented with intrathoracic IgG4-RD with pleuropericardial involvement. She showed initial improvement on prednisolone. Azathioprine and then mycophenolate failed to control relapses during steroid tapering. Her last relapse was treated by rituximab however, the patient developed acute fatal massive hemoptysis.

conclusionsPediatric IgG4-RD is a rare entity with pericardio-pulmonary affection as the rare of the rare. Usual treatment of prednisolone and steroid sparing agents should be used, with rituximab used as a rescue therapy, but fatal complications may occur.

Indexed as

Autoimmune DiseasesImmunoglobulin G4-Related DiseaseAdolescentChildFemaleHemoptysisHumansImmunoglobulin GPericardiumPrednisoloneRituximabImmunoglobulin GPrednisoloneRituximabIgG4-RDPediatric Immunoglobulin G-4 related diseasePericardial IgG4-RDPulmonary IgG4-RD

Identifiers

PMID36782218
PMCPMC9926825
OpenAlexW4320482357

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.