Evidence map›Paper›PMID 36782164›Full record

ArticleCardiovascular diabetology2023

Prevalence of prediabetes and undiagnosed diabetes in a large urban middle-aged population: the CARVAR 92 cohort.

Marie Hauguel-Moreau, Hélène Hergault, Laure Cazabat, Marion Pépin, Alain Beauchet, Vincent Aïdan, Mounir Ouadahi, Loïc Josseran, Mirella Hage, Christophe Rodon and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  2. Pharmacotherapy for obesity management in adults: 2025 clinical practice guideline update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
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  14. The Emerging Role of Prediabetes and Its Management: Focus on L-Arginine and a Survey in Clinical Practice.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Marie Hauguel-MoreauDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France. marie.hauguel@aphp.fr.
Hélène HergaultDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Laure CazabatDepartment of Endocrinology, Diabetology and Nutrition, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, France.
Marion PépinINSERM U-1018, CESP, Épidémiologie clinique, UVSQ, Villejuif, France.
Alain BeauchetPublic Health Department, APHP, UVSQ, Boulogne-Billancourt, France.
Vincent AïdanDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Mounir OuadahiDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Loïc JosseranDépartement Hospitalier d'Epidémiologie et de Santé Publique, AP-HP, GHU Paris Saclay, Hôpital Raymond-Poincaré, Garches, France.
Mirella HageDepartment of Endocrinology, Diabetology and Nutrition, Ambroise Paré Hospital, AP-HP, UVSQ, Boulogne-Billancourt, France.
Christophe RodonLocal Health insurance, Hauts de Seine Department, Paris, France.
Olivier DubourgDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Ziad MassyINSERM U-1018, CESP, Épidémiologie clinique, UVSQ, Villejuif, France.
Nicolas MansencalDepartment of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence Des Cardiomyopathies Et Des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), ACTION Study Group, Paris, 9, Avenue Charles de Gaulle, 92100, Boulogne-Billancourt, France.
Assistance Publique – Hôpitaux de Paris · FRHôpital Ambroise-Paré · FRCentre de recherche en Epidémiologie et Santé des Populations · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FRHôpital Raymond-Poincaré · FRLaboratoire Vision Action Cognition · FRl'Assurance Maladie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the prevalence of prediabetes and unknown diabetes and its long-term change in a large middle-aged urban population.

methodsWe conducted a screening campaign between 2007 and 2018 for cardiovascular risk factors in the western suburbs of Paris including subjects aged 40-70 (CARVAR 92). Among subjects who reported no previous diabetes, prediabetes and undiagnosed diabetes were defined as follows: fasting plasma glucose (FPG) ≥ 6.1 mmol/l (110 mg/dl) and < 7 mmol/l (126 mg/dl) for prediabetes according to WHO criteria (FPG between 5.6 and 6.9 mmol/l according to ADA criteria) and FPG ≥ 7.0 mmol/l for undiagnosed diabetes.

resultsOf the 32,721 subjects in the CARVAR 92 cohort, 32,675 were included in this analysis. The median age of the patients was 56 years [30, 94], 45.4% were male, 5.9% had known diabetes, 36.4% were overweight and 18.7% obese. Among patients without previously known diabetes (n = 30,759), 8.1% had prediabetes according to WHO criteria (27.2% according to ADA criteria) and 2.3% had diabetes. Subjects with prediabetes and unknown diabetes were more likely to be male, older, and overweight or obese than non-diabetic subjects. From 2007 to 2018, the prevalence of prediabetes, unknown diabetes, and known diabetes decreased, except for prediabetes which remained stable for people aged 55-64.

conclusionThe prevalence of prediabetes and unknown diabetes remains high but decreased during a 12-year period. About one-quarter of diabetes cases remain undiagnosed. Our results highlight that there is still a room for screening and cardiovascular prevention campaigns.

trial registrationIRB00012437.

Indexed as

Diabetes MellitusPrediabetic StateBlood GlucoseFastingFemaleHumansMaleMiddle AgedObesityOverweightPrevalenceRisk FactorsUrban PopulationBlood GlucosePrediabetesPrevalencePrimary preventionUnknown diabetes

Identifiers

PMID36782164
PMCPMC9926717
OpenAlexW4320483812

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.