ArticleBMC biology2023
XY sex determination in a cnidarian.
Article in BMC biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- A chromosome-level reference genome for the colonial marine hydrozoan Podocoryna americana.G3 (Bethesda, Md.) · 2026Article
- Sex Determination in Sponges.Molecular reproduction and development · 2026Review
- A chromosome-level genome assembly for the colonial marine hydrozoanbioRxiv : the preprint server for biology · 2026Article
- Article
- A positive feedback loop between germ cells and gonads induces and maintains sexual reproduction in a cnidarian.Science advances · 2025Article
- The genome of the colonial hydroidGenome research · 2024Article
- Pluripotent, germ cell competent adult stem cells underlie cnidarian regenerative ability and clonal growth.Current biology : CB · 2023Article
- Chromosome-level genome assembly of Hydractinia symbiolongicarpus.G3 (Bethesda, Md.) · 2023Article
- XY sex determination in a cnidarian.BMC biology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSex determination occurs across animal species, but most of our knowledge about its mechanisms comes from only a handful of bilaterian taxa. This limits our ability to infer the evolutionary history of sex determination within animals.
resultsIn this study, we generated a linkage map of the genome of the colonial cnidarian Hydractinia symbiolongicarpus and used it to demonstrate that this species has an XX/XY sex determination system. We demonstrate that the X and Y chromosomes have pseudoautosomal and non-recombining regions. We then use the linkage map and a method based on the depth of sequencing coverage to identify genes encoded in the non-recombining region and show that many of them have male gonad-specific expression. In addition, we demonstrate that recombination rates are enhanced in the female genome and that the haploid chromosome number in Hydractinia is n = 15.
conclusionsThese findings establish Hydractinia as a tractable non-bilaterian model system for the study of sex determination and the evolution of sex chromosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.