Evidence map›Paper›PMID 36782112›Full record

ArticleBMC gastroenterology2023

Hepatitis C micro-elimination through the retrieval strategy of patients lost to follow-up.

Cheng-Jen Chen, Yung-Hsin Huang, Chao-Wei Hsu, Yi-Cheng Chen, Ming-Ling Chang, Chun-Yen Lin, Yi-Hsien Shen, Rong-Nan Chien

Abstract read
In one paragraph

Article in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. A systematic PCR record-based re-call of HCV-RNA-positive people enables re-linkage to care and HCV elimination in Austria - The ELIMINATE project.Liver international : official journal of the International Association for the Study of the Liver · 2024
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheng-Jen Chen *Division of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Yung-Hsin Huang *Division of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Chao-Wei HsuDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. hsu2406@cgmh.org.tw.
Yi-Cheng ChenDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Ming-Ling ChangDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Chun-Yen LinDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Yi-Hsien ShenDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Rong-Nan ChienDivision of Hepato-Gastroenterology, Lin Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimWorld Health Organization sets up an ambitious and attainable goal to eliminate hepatitis C (HCV) by 2030. The previous diagnosed HCV patients lost to follow-up were considered as an important target group for HCV elimination. We conducted a call back program to retrieve the lost to follow-up HCV patients and link them to care in our hospital. By analyzing and comparing our result with that from other studies, we wish to improve our retrieval strategy and provide our experience to the general communities.

methodsA list of the patients with a medical record showing seropositive for antibody to HCV (anti-HCV Ab) from 2004 to 2017 was retrieved by the department of intelligent technology of our hospital. Three dedicated staff members reviewed the patients' electronic medical records (EMRs) and recruited the patient lost follow-up to the call back program. The staff members contacted the qualified patients by telephone and inquired about their opinions for treating their chronic HCV infection. We also informed the patients about the retrieval strategy and why we contact them. As our National Health Insurance request, we gave all patient one informed consent for hepatitis C treatment. Informed consents have been obtained from all patients. Referrals to our gastroenterology unit (GU) were arranged for the patients who would like to continue their chronic HCV care in our hospital.

resultsThere were 31,275 anti-HCV positive patients. We included 11,934 patients (38.2%) into the call back system and contacted them by telephone. Based on the response to our call, we ascertained 1277 eligible cases (10.7%) for retrieval. The patients who were younger (< 55), lived in Taoyaun City or had tested positive for anti-HCV Ab at the department of internal medicine department had an increased rate of successful call back. There were 563 patients (44.1%) returning to our GU. Of them, 354 patients (62.9%) were positive for HCV viremia. 323 patients (91.2%) received the DAAs treatment. The SVR12 with Grazoprevir + elbasvir, Glecaprevir + pibrentasvir, Sofosbuvir + ledipasvir and Sofosbuvir + velpatasvir were 97.9%, 98.8%, 100% and 97.5%, respectively.

conclusionsCall back system can expand our reach to those unaware or ignoring chronic HCV infection patients and link them to treatment.

Indexed as

Hepatitis CHepatitis C, ChronicAntiviral AgentsDrug Therapy, CombinationHepacivirusHumansLost to Follow-UpSofosbuvirAntiviral AgentsSofosbuvirDirect-acting antiviralsHepatitis CMicro-eliminationRetrieval strategy

Identifiers

PMID36782112
PMCPMC9926801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.