Evidence map›Paper›PMID 36782094›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants.

Sepehr Talebian, Bárbara Mendes, João Conniot, Syamak Farajikhah, Fariba Dehghani, Zhongyan Li, Diogo Bitoque, Gabriela Silva, Sina Naficy, João Conde and 1 more

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  17. [Preparation of berberine-naringin dual drug-loaded composite microspheres and evaluation of their antibacterial-osteogenic properties].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Article
  18. Article
  19. Transformative Materials for Interfacial Drug Delivery.Advanced healthcare materials · 2023
    Article
  20. Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sepehr TalebianSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.ORCID 0000-0002-4735-0986
Bárbara MendesToxOmics, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal.
João ConniotToxOmics, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal.
Syamak FarajikhahSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.
Fariba DehghaniSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.
Zhongyan LiSchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.
Diogo BitoqueToxOmics, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal.
Gabriela SilvaToxOmics, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal.
Sina NaficySchool of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW, 2006, Australia.
João CondeToxOmics, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal.ORCID 0000-0001-8422-6792
Gordon G WallaceIntelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, Sydney, NSW, 2522, Australia.ORCID 0000-0002-0381-7273

Funding

Australian Research Council DP200102164Australian Research Council Centre of Excellence program CE 140100012European Research Council ERC-StG-2019-848325
6 · The paper itself

Abstract

The deployment of structures that enable localized release of bioactive molecules can result in more efficacious treatment of disease and better integration of implantable bionic devices. The strategic design of a biopolymeric coating can be used to engineer the optimal release profile depending on the task at hand. As illustrative examples, here advances in delivery of drugs from bone, brain, ocular, and cardiovascular implants are reviewed. These areas are focused to highlight that both hard and soft tissue implants can benefit from controlled localized delivery. The composition of biopolymers used to achieve appropriate delivery to the selected tissue types, and their corresponding outcomes are brought to the fore. To conclude, key factors in designing drug-loaded biopolymeric coatings for biomedical implants are highlighted.

Indexed as

Prostheses and ImplantsBiopolymersBiopolymersbiopolymerscontrolled releasedrug deliverymedical Implants

Identifiers

PMID36782094
PMCPMC10131825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.