Evidence map›Paper›PMID 36781977›Full record

ArticleThe Journal of antibiotics2023

In vitro antibacterial effects of combination of ciprofloxacin with compounds isolated from Streptomyces luteireticuli NIIST-D75.

Abdul Rasheed Safiya Jesmina, D K Induja, Thankappan Drissya, Chakiniplackal Rajan Sruthi, Kozhiparambil Gopalan Raghu, Shijulal Nelson-Sathi, Bhaskaran Nair Saraswathy Amma Dileep Kumar, Ravi S Lankalapalli

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Enhancing the destruction ofFrontiers in cellular and infection microbiology · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Abdul Rasheed Safiya JesminaAgro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India.
D K IndujaAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Thankappan DrissyaAgro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India.
Chakiniplackal Rajan SruthiAgro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India.
Kozhiparambil Gopalan RaghuAgro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India.
Shijulal Nelson-SathiTransdisciplinary Biology, Bioinformatics Laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, India.
Bhaskaran Nair Saraswathy Amma Dileep KumarAgro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, 695019, India. kumardileep@niist.res.in.
Ravi S LankalapalliAcademy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. ravishankar@niist.res.in.ORCID http://orcid.org/0000-0001-8223-7674
National Institute for Interdisciplinary Science and Technology · INRajiv Gandhi Centre for Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three phenazines, 1-methoxyphenazine (1), methyl-6-methoxyphenazine-1-carboxylate (2), 1,6-dimethoxyphenazine (4), and a 2,3-dimethoxy benzamide (3) were isolated from the Streptomyces luteireticuli NIIST-D75, and the antibacterial effects of compounds 1-3, each in combination with ciprofloxacin, were investigated. The in vitro antibacterial activity was assessed by microdilution, checkerboard, and time-kill assay against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi. According to the checkerboard assay results, each combination of compounds 1, 2 and 3 with ciprofloxacin resulted in a significantly lower minimum inhibitory concentrations (MICs) of 0.02-1.37 µg ml

Indexed as

CiprofloxacinStaphylococcus aureusAnti-Bacterial AgentsBenzamidesDrug SynergismEscherichia coliMicrobial Sensitivity TestsPhenazinesStreptomyces1,6-dimethoxyphenazine2,3-dimethoxybenzamideAnti-Bacterial AgentsBenzamidesCiprofloxacinPhenazines

Identifiers

PMID36781977
OpenAlexW4320482696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.