Evidence map›Paper›PMID 36781814›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2023

Impact of opioids on treatment response among idiopathic esophagogastric junction outflow obstruction patients: A retrospective cohort study.

Wojciech Blonski, Ambuj Kumar, John Jacobs, John Feldman, Joel E Richter

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wojciech BlonskiJoy McCann Culverhouse Center for Swallowing Disorders, Division of Digestive Diseases and Nutrition, University of South Florida Health Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC 72, Tampa, FL, 33612, USA.
Ambuj KumarResearch Methodology and Biostatistics Core, Office of Research, Department of Internal Medicine, University of South Florida Health Morsani College of Medicine, Tampa, FL, USA.
John JacobsJoy McCann Culverhouse Center for Swallowing Disorders, Division of Digestive Diseases and Nutrition, University of South Florida Health Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC 72, Tampa, FL, 33612, USA.
John FeldmanDepartment of Radiology, University of South Florida Health Morsani College of Medicine, Tampa, FL, USA.
Joel E RichterJoy McCann Culverhouse Center for Swallowing Disorders, Division of Digestive Diseases and Nutrition, University of South Florida Health Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC 72, Tampa, FL, 33612, USA. jrichte1@usf.edu.
University of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal dysmotility has been attributed to opioid use. The goal was to assess the differences in pre- and post-treatment timed-barium esophagram (TBE) barium heights at 1 and 5 minutes and symptomatic response to treatment in esophagogastric junction outflow obstruction (EGJOO) patients according to opioid use status.

methodsWe performed a retrospective cohort study. Consecutive patients with EGJOO were eligible for inclusion. Data were collected on demographics, pre and post-treatment 1 and 5 minutes TBE barium heights and symptom outcomes. Groups were compared according to opioid use.

resultsThirty-one EGJOO patients met the inclusion criteria. All patients were treated with pneumatic dilation. Of the 31 patients, 11 (35%) had opioid exposure and 20 (65%) did not. The median follow-up post-treatment was two months (range 1-47 months). There was no statistically significant difference in post-treatment outcomes for opioid exposed vs. unexposed groups. The median per cent decrease in the TBE barium height at 1 minute was 100% for the opioid exposed vs. 71% for the unexposed group (p = 0.92). The median per cent decrease in the TBE barium height at 5 minutes was zero % for the opioid exposed and unexposed groups (p = 0.67). The incidence of symptomatic improvement was 82% (9/11) for the opioid exposed group vs 95% (19/20) for the unexposed group (p = 0.28).

conclusionsPatients with EGJOO seem to respond to treatment similarly regardless of being on opioids.

Indexed as

Esophageal AchalasiaEsophageal Motility DisordersStomach DiseasesAnalgesics, OpioidBariumEsophagogastric JunctionHumansManometryRetrospective StudiesAnalgesics, OpioidBariumBarium heightChicago ClassificationEckardt symptom scoreEsophageal dysmotilityEsophagogastric junction outflow obstructionHigh resolution manometryLES relaxationOpioidsPneumatic dilationTimed barium esophagram

Identifiers

PMID36781814
OpenAlexW4320483916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.