ReviewCerebellum (London, England)2024
Cerebellum Lecture: the Cerebellar Nuclei-Core of the Cerebellum.
Review in Cerebellum (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
50 citing papers in PubMed, 75 citations in OpenAlex.
- Viral Tracing Gone Viral: Expanded Possibilities Call for Increased Caution in Describing Cerebellar Network Connections.Cerebellum (London, England) · 2026Review
- Impact of Losartan Nanoparticles on Carbon Tetrachloride-induced Cerebellar Injury in Rats: Association with Alterations in RIPK1/RIPK3/MLKL Necroptosis Markers.Molecular neurobiology · 2026Article
- Anatomy of Cerebro-cerebellar Circuits in Motor Control.Cerebellum (London, England) · 2026Review
- Molecular and Cellular Mechanisms of Synaptogenesis and Synaptic Refinement During Cerebellar Circuit Formation.International journal of molecular sciences · 2026Review
- Cerebellum-inspired neural network of supervised learning with tensor-based sparse coding for multi-class classification.PLoS computational biology · 2026Article
- Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.Scientific reports · 2026Article
- Specialized outputs and behavioral contributions of Purkinje cell subtypes.bioRxiv : the preprint server for biology · 2026Article
- Steady-state Purkinje cell activity has limited predictive power for cerebellar output in disease.The Journal of physiology · 2026Article
- Asymmetric scaling of cerebellar cortex and deep nuclei reshapes input-output architecture across primates.Research square · 2026Article
- Predicting individual differences of fear and cognitive learning and extinction.Nature communications · 2026Article
- Nonuniform scaling of cerebellar cortical-nuclear architecture across primates revealed by cross-species atlases.bioRxiv : the preprint server for biology · 2026Article
- Human and mouse cerebellar inhibitory circuits in dystonic crisis and their modulation with therapeutic stimulation.bioRxiv : the preprint server for biology · 2026Article
- Bidirectional Modulation of Beam Traversal Performance by Acetylcholine in the Cerebellar Nuclei.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The evolution of gene regulation in mammalian cerebellum development.Science (New York, N.Y.) · 2026Article
- Brain-wide mapping of developmental trajectories of cerebellar efferent projections.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The legacy of Rudolf Nieuwenhuys in perspective.Brain structure & function · 2025Article
- Cell replacement in the degenerating cerebellum: a historical essay of discovery.Journal of neurology · 2025Review
- Cerebellar organoids model cell type-specific FOXP2 expression during human cerebellar development.Disease models & mechanisms · 2025Article
- Glutamatergic Neurons in the Cerebellar Lateral Nucleus Contribute to Motor Deficits Induced by Chronic Sleep Disturbance.Brain sciences · 2025Article
- Characterization of Perineuronal Nets in the Human Cerebellum.Cerebellum (London, England) · 2025Article
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 7 countries.
Funding
Abstract
The cerebellum is a key player in many brain functions and a major topic of neuroscience research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum, are often overlooked. This neglect is because research on the cerebellum typically focuses on the cortex and tends to treat the CN as relatively simple output nuclei conveying an inverted signal from the cerebellar cortex to the rest of the brain. In this review, by adopting a nucleocentric perspective we aim to rectify this impression. First, we describe CN anatomy and modularity and comprehensively integrate CN architecture with its highly organized but complex afferent and efferent connectivity. This is followed by a novel classification of the specific neuronal classes the CN comprise and speculate on the implications of CN structure and physiology for our understanding of adult cerebellar function. Based on this thorough review of the adult literature we provide a comprehensive overview of CN embryonic development and, by comparing cerebellar structures in various chordate clades, propose an interpretation of CN evolution. Despite their critical importance in cerebellar function, from a clinical perspective intriguingly few, if any, neurological disorders appear to primarily affect the CN. To highlight this curious anomaly, and encourage future nucleocentric interpretations, we build on our review to provide a brief overview of the various syndromes in which the CN are currently implicated. Finally, we summarize the specific perspectives that a nucleocentric view of the cerebellum brings, move major outstanding issues in CN biology to the limelight, and provide a roadmap to the key questions that need to be answered in order to create a comprehensive integrated model of CN structure, function, development, and evolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.