Evidence map›Paper›PMID 36781430›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2023

RBM3 is associated with acute lung injury in septic mice and patients via the NF-κB/NLRP3 pathway.

Feiyu Long, Liren Hu, Yingxu Chen, Xiaoxia Duan, Keliang Xie, Jianguo Feng, Maohua Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Augmenting the Endogenous RBM3 Response Protects Against Burn-Induced Acute Kidney Injury by Enhancing Macrophage-Mediated Resolution of Inflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Feiyu Long *Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.
Liren Hu *Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.
Yingxu Chen *Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.
Xiaoxia DuanDepartment of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.
Keliang XieDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Jianguo FengDepartment of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China. fengjianguo@swmu.edu.cn.
Maohua WangDepartment of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China. wangmaohua@swmu.edu.cn.
Southwest Medical University · CNAffiliated Hospital of Southwest Medical University · CNTianjin Medical University General Hospital · CNWest China Hospital of Sichuan University · CN

Funding

Sichuan Science and Technology Program 2022YFS0632the joint foundation of Luzhou government and Southwest Medical University 2021LZXNYD-J28
6 · The paper itself

Abstract

Sepsis refers to host response disorders caused by infection, leading to life-threatening organ dysfunction. RNA-binding motif protein 3 (RBM3) is an important cold-shock protein that is upregulated in response to mild hypothermia or hypoxia. In this study, we aimed to investigate whether RBM3 is involved in sepsis-associated acute lung injury (ALI). Intraperitoneal injection of LPS (10 mg/kg) was performed in wild type (WT) and RBM3 knockout (KO, RBM3

Indexed as

Acute Lung InjurySepsisAnimalsHumansInflammasomesLipopolysaccharidesMiceMice, Inbred C57BLNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinRNA-Binding ProteinsSulfonamidesInflammasomesLipopolysaccharidesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseRbm3 protein, mouseRNA-Binding ProteinsSulfonamidesAcute lung injuryNF-κB and NLRP3RBM3Sepsis

Identifiers

PMID36781430
OpenAlexW4320482386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.