Evidence map›Paper›PMID 36781414›Full record

ArticleJournal of the International Neuropsychological Society : JINS2023

The role of gender in cognitive outcomes from stroke.

Emma Brandt, Sachinkumar Singh, Mark Bowren, Amol Bhagvathi, Daniel Tranel, Aaron D Boes

Open access · hybridAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emma BrandtDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA52242, USA.ORCID 0000-0002-1814-7030
Sachinkumar SinghDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA52242, USA.
Mark BowrenDepartment of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA52242, USA.ORCID 0000-0003-3304-6921
Amol BhagvathiDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA52242, USA.
Daniel TranelDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA52242, USA.
Aaron D BoesDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA52242, USA.
University of Iowa · US

Funding

The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI O'DOHERTY, JOHN P · 2012 to 2021
$18.6M
University of Iowam - Whole Body 7T MRI ScannerS10RR028821 · NCRR · UNIVERSITY OF IOWA · PI MAGNOTTA, VINCENT A · 2010 to 2010
$8.0M
Stroke, Brain Networks, and BehaviorR01NS095741 · NINDS · WASHINGTON UNIVERSITY · PI CORBETTA, MAURIZIO · 2015 to 2019
$3.0M
Predicting Cognitive Outcomes from Stroke Based on Lesion LocationR01NS114405 · NINDS · UNIVERSITY OF IOWA · PI BOES, AARON D · 2020 to 2024
$2.1M
Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
Investigating the Effects of Transcranial Magnetic Stimulation with Intracranial EEG in HumansR21MH120441 · NIMH · UNIVERSITY OF IOWA · PI BOES, AARON D, OYA, HIROYUKI · 2019 to 2020
$425k
NCRR NIH HHS S10 RR028821NIGMS NIH HHS T32 GM108540NIMH NIH HHS P50 MH094258NIMH NIH HHS R21 MH120441NINDS NIH HHS R01 NS095741NINDS NIH HHS R01 NS114405
6 · The paper itself

Abstract

objectiveStroke can cause cognitive impairment, which can lead to challenges returning to day-to-day activities. Knowing what factors are associated with cognitive impairment post-stroke can be useful for predicting outcomes and guiding rehabilitation. One such factor is gender: previous studies are inconclusive as to whether gender influences cognitive outcomes post-stroke. Accounting for key variables, we examined whether there are gender differences in cognitive outcomes after stroke.

methodWe analyzed data from neuropsychological assessments of 237 individuals tested in the chronic epoch (≥ 3 months) following ischemic stroke. Using ANCOVA and linear mixed modeling, we examined gender as a predictor of cognition as measured by general cognitive ability (g), Full-Scale IQ, and 18 cognitive tests, controlling for age at stroke onset, education, premorbid intelligence, and lesion volume.

resultsThere were no significant gender differences in overall cognitive outcomes as measured by g (

conclusionsOur findings indicate that men and women have similar overall cognitive outcomes after stroke, when demographic and lesion factors are accounted for. Although men and women differed in their performance on some individual cognitive tests, neither gender performed systematically better or worse. However, for learning, working memory, and verbal knowledge/comprehension, gender may be an important predictor of outcome post-stroke.

Indexed as

Cognition DisordersStrokeAdultCognitionFemaleHumansIntelligence TestsMaleNeuropsychological Testsggender differencesIQischemic strokerecoverysex

Identifiers

PMID36781414
PMCPMC10757593
OpenAlexW4320480833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.