ArticleeNeuro2023
Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics.
Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Neurochemical imaging reveals changes in dopamine dynamics with photoperiod in a seasonally social vole species.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Identification of photoperiod as a regulator of dopamine-mediated behavior in female mice.Neurobiology of sleep and circadian rhythms · 2025Article
- Photoperiod Management in Farm Animal Husbandry: A Review.Animals : an open access journal from MDPI · 2025Review
- Perinatal Photoperiod Has Long-Term Effects on the Rest-Activity Cycle and Sleep in Male and Female Mice.Journal of biological rhythms · 2025Article
- Beyond vision: effects of light on the circadian clock and mood-related behaviours.Npj biological timing and sleep · 2025Review
- Transcriptomic Plasticity of the Circadian Clock in Response to Photoperiod: A Study in Male Melatonin-Competent Mice.Journal of biological rhythms · 2024Article
- Seasonal variation in D2/3 dopamine receptor availability in the human brain.European journal of nuclear medicine and molecular imaging · 2024Article
- Comparison of dopamine release and uptake parameters across sex, species and striatal subregions.The European journal of neuroscience · 2024Article
- Effects of age and sex on photoperiod modulation of nucleus accumbens monoamine content and release in adolescence and adulthood.Neurobiology of sleep and circadian rhythms · 2024Article
- Review
- Kappa opioid receptor agonist U50,488 inhibits dopamine more in caudal than rostral nucleus accumbens core.Basic & clinical pharmacology & toxicology · 2023Article
- Are There Prevalent Sex Differences in Psychostimulant Use Disorder? A Focus on the Potential Therapeutic Efficacy of Atypical Dopamine Uptake Inhibitors.Molecules (Basel, Switzerland) · 2023Review
- Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study.Frontiers in physiology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Circadian photoperiod, or day length, changes with the seasons and influences behavior to allow animals to adapt to their environment. Photoperiod is also associated with seasonal rhythms of affective state, as evidenced by seasonality of several neuropsychiatric disorders. Interestingly, seasonality tends to be more prevalent in women for affective disorders such as major depressive disorder and bipolar disorder (BD). However, the underlying neurobiological processes contributing to sex-linked seasonality of affective behaviors are largely unknown. Mesolimbic dopamine input to the nucleus accumbens (NAc) contributes to the regulation of affective state and behaviors. Additionally, sex differences in the mesolimbic dopamine pathway are well established. Therefore, we hypothesize that photoperiod may drive differential modulation of NAc dopamine in males and females. Here, we used fast-scan cyclic voltammetry (FSCV) to explore whether photoperiod can modulate subsecond dopamine signaling dynamics in the NAc core of male and female mice raised in seasonally relevant photoperiods. We found that photoperiod modulates dopamine signaling in the NAc core, and that this effect is sex-specific to females. Both release and uptake of dopamine were enhanced in the NAc core of female mice raised in long, summer-like photoperiods, whereas we did not find photoperiodic effects on NAc core dopamine in males. These findings uncover a potential neural circuit basis for sex-linked seasonality in affective behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.