Evidence map›Paper›PMID 36781143›Full record

ArticleJournal of affective disorders2023

Suicidal urges and attempted suicide at multiple time scales in borderline personality disorder.

Aleksandra Kaurin, Alexandre Y Dombrovski, Michael N Hallquist, Aidan G C Wright

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Aleksandra KaurinDepartment of Psychology, University of Wuppertal, Germany. Electronic address: kaurin@uni-wuppertal.de.
Alexandre Y DombrovskiDepartment of Psychiatry, University of Pittsburgh School of Medicine, USA.
Michael N HallquistDepartment of Psychology and Neuroscience, University of North Carolina, Chapel Hill, USA.
Aidan G C WrightDepartment of Psychology, University of Pittsburgh, USA.
University of Pittsburgh · USUniversity of North Carolina at Chapel Hill · USUniversity of Wuppertal · DE

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPDR01MH048463 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 1992 to 2026
$13.9M
Reward Learning in Late-Life Suicidal BehaviorR01MH100095 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 2014 to 2026
$6.8M
Neurocomputational mechanisms of impaired social decision-making in borderline personalityR01MH119399 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HALLQUIST, MICHAEL NELSON · 2019 to 2024
$2.5M
NCATS NIH HHS UL1 TR001857NIMH NIH HHS L30 MH101760NIMH NIH HHS R01 MH048463NIMH NIH HHS R01 MH100095NIMH NIH HHS R01 MH119399
6 · The paper itself

Abstract

backgroundThere is strong evidence for an enduring suicidal diathesis among individuals with a history of suicide attempts, particularly among people diagnosed with borderline personality disorder (BPD). However, the progression of suicidal crises among people predisposed to suicidal behavior remains poorly understood.

methodsVia multilevel structural equation modeling we tested the hypothesis that a history of attempted suicide predicts a stronger dynamic link between affect and impulsivity with suicidal ideation (i.e., suicidal urges) - both moment-to-moment and day-to-day. 153 patients diagnosed with BPD, 105 of whom had a history of medically serious suicide attempts completed a 21-day ecological momentary assessment protocol (17,926 total assessments).

resultsIndividuals with higher average levels of negative affect reported more suicidal thoughts. Moments characterized by more negative affect, hostility, impulsivity, and less positive affect were also characterized by elevated suicidal ideation. For hostility and positive affect, these significant links generalized to the daily level. At the same time, for negative affect and hostility the within-person coupling was stronger among attempters in comparison to non-attempters, and these effects did not significantly differ across timescales. LIMITATIONS: Follow-up studies replicating our findings of the dysregulation-suicidality nexus in clinically more diverse samples are needed.

conclusionsThe diathesis for suicidal behavior manifests in tighter dynamic links between negative affect or hostility and suicidal ideation. Because these within-person links were amplified in attempters compared to non-attempters, differential coupling patterns may index potentially lethal processes that generalize beyond BPD reflecting distinct diathesis components.

Indexed as

Borderline Personality DisorderSuicide, AttemptedDisease SusceptibilityHostilityHumansSuicidal IdeationBorderline personality disorderEcological momentary assessmentMultilevel structural equation modelingSuicidal ideation

Identifiers

PMID36781143
PMCPMC10693674
OpenAlexW4320035489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.