Evidence map›Paper›PMID 36780769›Full record

ArticleRedox biology2023

Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H

Zsolt Combi, László Potor, Péter Nagy, Katalin Éva Sikura, Tamás Ditrói, Eszter Petra Jurányi, Klaudia Galambos, Tamás Szerafin, Péter Gergely, Matthew Whiteman and 7 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. CoQExperimental & molecular medicine · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. The Role of NOTCH Pathway Genes in the Inherited Susceptibility to Aortic Stenosis.Journal of cardiovascular development and disease · 2024
    Article
  16. Article
  17. Article
  18. Models for calcific aortic valve disease in vivo and in vitro.Cell regeneration (London, England) · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Zsolt CombiDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary; ELKH-UD Vascular Pathophysiology Research Group, University of Debrecen, 11003, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary.
László PotorDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary; ELKH-UD Vascular Pathophysiology Research Group, University of Debrecen, 11003, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary.
Péter NagyDepartment of Molecular Immunology and Toxicology and the National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary; Institute of Chemistry, Faculty of Science and Technology, University of Debrecen, Debrecen, Hungary; Department of Anatomy and Histology, ELKH Laboratory of Redox Biology, University of Veterinary Medicine, Budapest, Hungary.
Katalin Éva SikuraDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary; ELKH-UD Vascular Pathophysiology Research Group, University of Debrecen, 11003, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary.
Tamás DitróiDepartment of Molecular Immunology and Toxicology and the National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
Eszter Petra JurányiDepartment of Molecular Immunology and Toxicology and the National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary; Doctoral School of Molecular Medicine, Semmelweis University, Budapest, Hungary.
Klaudia GalambosKálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary; Department of Molecular Immunology and Toxicology and the National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
Tamás SzerafinDepartment of Cardiac Surgery, Faculty of Medicine, University of Debrecen, Hungary.
Péter GergelyInstitute of Forensic Medicine, Faculty of Medicine, University of Debrecen, Hungary.
Matthew WhitemanUniversity of Exeter Medical School, St. Luke's Campus, Magdalen Road, Exeter, EX1 2LU, UK.
Roberta TorregrossaUniversity of Exeter Medical School, St. Luke's Campus, Magdalen Road, Exeter, EX1 2LU, UK.
Yuchao DingDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary.
Lívia BekeInstitute of Pathology, Faculty of Medicine, University of Debrecen, Hungary.
Zoltán HendrikInstitute of Forensic Medicine, Faculty of Medicine, University of Debrecen, Hungary.
Gábor MéhesInstitute of Pathology, Faculty of Medicine, University of Debrecen, Hungary.
György BallaELKH-UD Vascular Pathophysiology Research Group, University of Debrecen, 11003, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary; Department of Pediatrics, Faculty of Medicine, University of Debrecen, Hungary.
József BallaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Hungary; ELKH-UD Vascular Pathophysiology Research Group, University of Debrecen, 11003, Hungary; Kálmán Laki Doctoral School, University of Debrecen, Debrecen, Hungary. Electronic address: balla.jozsef@med.unideb.hu.
University of Debrecen · HUUniversity of Exeter · GBNational Institute of Oncology · HUSemmelweis University · HU

Funding

Medical Research Council MR/S002626/1
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Aortic Valve StenosisCalcinosisHydrogen SulfideAortic ValveCells, CulturedHumansMitochondriaMitochondrial ProteinsNucleocytoplasmic Transport ProteinsTumor Necrosis Factor-alphaETHE1 protein, humanHydrogen SulfideMitochondrial ProteinsNucleocytoplasmic Transport ProteinsTumor Necrosis Factor-alphaArteriosclerosisChronic kidney diseaseHydrogen sulfideMitochondrial H(2)S catabolismPhosphateValvular inflammationVascular calcification

Identifiers

PMID36780769
PMCPMC9947110
OpenAlexW4319601382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.