Evidence map›Paper›PMID 36780768›Full record

ArticleDrug and alcohol dependence2023

Community selected strategies to reduce opioid-related overdose deaths in the HEALing (Helping to End Addiction Long-term

Redonna Chandler, Edward V Nunes, Sylvia Tan, Patricia R Freeman, Alexander Y Walley, Michelle Lofwall, Emmanuel Oga, LaShawn Glasgow, Jennifer L Brown, Laura Fanucchi and 6 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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  11. Structural Racism and Coalition Decision-Making: A Qualitative Study of Opioid Prevention and Treatment Implementation.Prevention science : the official journal of the Society for Prevention Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Redonna ChandlerNational Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA. Electronic address: redonna.chandler@nih.gov.
Edward V NunesColumbia University Irving Medical Center and New York State Psychiatric Institute, New York, NY, USA.
Sylvia TanRTI International, Research Triangle Park, NC, USA.
Patricia R FreemanDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Alexander Y WalleyGrayken Center for Addiction, Clinical Addiction Research Education Unit, Boston Medical Center Boston, MA, USA.
Michelle LofwallCollege of Medicine, University of Kentucky Center on Drug and Alcohol Research, Lexington, KY, USA.
Emmanuel OgaRTI International, Research Triangle Park, NC, USA.
LaShawn GlasgowRTI International, Research Triangle Park, NC, USA.
Jennifer L BrownDepartment of Psychological Sciences, Purdue University, West Lafayette, IN, USA.
Laura FanucchiCollege of Medicine, University of Kentucky Center on Drug and Alcohol Research, Lexington, KY, USA.
Donna BeersGrayken Center for Addiction, Clinical Addiction Research Education Unit, Boston Medical Center Boston, MA, USA.
Timothy HuntColumbia University School of Social Work, 1255 Amsterdam Avenue, New York, NY, USA.
Rachel Bowers-SwordGrayken Center for Addiction, Clinical Addiction Research Education Unit, Boston Medical Center Boston, MA, USA.
Carter RoeberSubstance Abuse and Mental Health Services Administration, Rockville, MD, USA.
Trevor BakerGrayken Center for Addiction, Clinical Addiction Research Education Unit, Boston Medical Center Boston, MA, USA.
T John WinhusenDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Center for Addiction Research, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateUM1DA049415 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA, GILBERT, LOUISA · 2019 to 2023
$77.3M
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementUM1DA049417 · NIDA · OHIO STATE UNIVERSITY · PI FREISTHLER, BRIDGET J, WINHUSEN, T JOHN · 2019 to 2023
$66.3M
HEALing Communities Study Health Equity ResearchUM1DA049394 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI GLASGOW, LASHAWN, OGA, EMMANUEL AJA · 2019 to 2023
$40.6M
Training Program on HIV and Substance Use in the Criminal Justice SystemT32DA037801 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Nabila El-Bassel, Lisa R Metsch · 2014 to 2026
$5.7M
NIDA NIH HHS T32 DA037801NIDA NIH HHS UM1 DA049394NIDA NIH HHS UM1 DA049406NIDA NIH HHS UM1 DA049412NIDA NIH HHS UM1 DA049415NIDA NIH HHS UM1 DA049417
6 · The paper itself

Abstract

The Helping End Addictions Long Term (HEALing) Communities Study (HCS) seeks to significantly reduce overdose deaths in 67 highly impacted communities in Kentucky (KY), Massachusetts (MA), New York (NY), and Ohio (OH) by implementing evidence-based practices (EBPs) to reduce overdose deaths. The Opioid-overdose Reduction Continuum of Care Approach (ORCCA) organizes EBP strategies under three menus: Overdose Education and Naloxone Distribution (OEND), Medication Treatment for Opioid Use Disorder (MOUD), and Safer Prescribing and Dispensing Practices (SPDP). The ORCCA sets requirements for strategy selection but allows flexibility to address community needs. This paper describes and compiles strategy selection and examines two hypotheses: 1) OEND selections will differ significantly between communities with higher versus lower opioid-involved overdose deaths; 2) MOUD selections will differ significantly between urban versus rural settings.

methodsWave 1 communities (n = 33) provided data on EBP strategy selections. Selections were recorded as a combination of EBP menu, sector (behavioral health, criminal justice, and healthcare), and venue (e.g., jail, drug court, etc.); target medication(s) were recorded for MOUD strategies. Strategy counts and proportions were calculated overall and by site (KY, MA, NY, OH), setting (rural/urban), and opioid-involved overdose deaths (high/low).

resultsStrategy selection exceeded ORCCA requirements across all 33 communities, with OEND strategies accounting for more (40.8%) than MOUD (35.1%), or SPDP (24.1%) strategies. Site-adjusted differences were not significant for either hypothesis related to OEND or MOUD strategy selection.

conclusionsHCS communities selected strategies from the ORCCA menu well beyond minimum requirements using a flexible approach to address unique needs.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidHumansNaloxoneSuccinimidesAnalgesics, OpioidNaloxoneN-succinimidyl 3-(2-pyridyldithio)propionateSuccinimidesHEALing Communities StudyMedication for opioid use disorder (MOUD)NaloxoneOpioid-overdose Reduction Continuum of Care Approach (ORCCA)Opioid prescribing

Identifiers

PMID36780768
PMCPMC10291332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.