Evidence map›Paper›PMID 36780586›Full record

ArticleOcular immunology and inflammation2024

Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.

Albert Liao, Caroline Fajoles-Vasseneix, Aditya Rali, Laura Ward, Alcides Fernandes, Purnima S Patel, Ghazala O'Keefe, Jessica G Shantha, Steven Yeh

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Ocular immunology and inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Albert LiaoEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Caroline Fajoles-VasseneixEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Aditya RaliEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Laura WardDepartment of Epidemiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Alcides FernandesEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Purnima S PatelEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Ghazala O'KeefeEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Jessica G ShanthaEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Steven YehEmory Eye Center, Uveitis Service, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory Eye Center · USEmory University · US

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI NICKERSON, JOHN M · 1986 to 2025
$15.3M
Pathogenesis of Uveitis in Ebola Virus Disease SurvivorsR01EY029594 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI YEH, STEVEN · 2019 to 2023
$2.9M
Ophthalmic Disease and Laboratory Surveillance in a Viral Hemorrhagic Fever ZoneK23EY030158 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHANTHA, JESSICA · 2019 to 2023
$1.2M
NEI NIH HHS K23 EY030158NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY029594
6 · The paper itself

Abstract

purposeTo compare visual outcomes, ocular complications and therapies for patients with scleritis-associated intraocular inflammation (SAI) and patients with isolated scleritis (IS).

resultsA total of 52 patients (36 with SAI and 16 with IS) were reviewed. Mean age (standard deviation) at presentation was 48.4 years old (± 15.4) in the SAI group and 53 years old (± 17.1) in the IS group (p = .37). Visual acuity was worse at presentation and last visit for patients with SAI compared to IS (p = .04). Patients in the SAI group developed greater posterior segment complications than in the IS group (p = .002).

conclusionsScleritis with intraocular inflammation was associated with a higher rate of visual morbidity compared to isolated scleritis. More aggressive management strategies may be needed for patients who present with scleritis associated with inflammation.

Indexed as

ScleritisVisual AcuityAdultAgedFemaleGlucocorticoidsHumansMaleMiddle AgedMorbidityRetrospective StudiesGlucocorticoidsImmunosuppressionocular diseaseocular manifestationscleritissclerouveitisuveitis

Identifiers

PMID36780586
PMCPMC10423300
OpenAlexW4320482417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.