Evidence map›Paper›PMID 36780557›Full record

Trial reportPloS one2023

Clinical and radiological effects of Corticosteroid injection combined with deep transverse friction massage and Mill's manipulation in lateral epicondylalgia-A prospective, randomized, single-blinded, sham controlled trial.

Gopal Nambi, Mshari Alghadier, Anju Verma, Osama R Aldhafian, Naif N Alshahrani, Ayman K Saleh, Mohamed A Omar, Tohamy G T Hassan, Mohamed Nagah Ahmed Ibrahim, Hassan Fathy El Behairy

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06500585 (Effects of Mill's Manipulation Along With Muscle Energy Technique in Lateral Epicondylitis), which is not on this map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06500585 nacompletednot on this map

Effects of Mill's Manipulation Along With Muscle Energy Technique in Lateral Epicondylitis

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled28ConditionsLateral EpicondylitisArmsMill's Manipulation, Mill's Manipulation and Muscle Energy Technique
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Manual therapy and exercise for lateral elbow pain.The Cochrane database of systematic reviews · 2024
    Pooled it
  4. Trial
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Gopal NambiDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.ORCID 0000-0002-4203-5506
Mshari AlghadierDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.ORCID 0000-0003-3686-8074
Anju VermaDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.
Osama R AldhafianDepartment of Surgery, College of Medicine, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.
Naif N AlshahraniOrthopedic Surgery Department, King Fahad medical city, Ministry of Health, Riyadh, Saudi Arabia.
Ayman K SalehDepartment of Surgery, College of Medicine, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.
Mohamed A OmarFaculty of Medicine for Girls, Department of Orthopedic Surgery, Al-Azhar University, Cairo, Egypt.
Tohamy G T HassanFaculty of Medicine for Girls, Department of Orthopedic Surgery, Al-Azhar University, Cairo, Egypt.
Mohamed Nagah Ahmed IbrahimFaculty of Medicine for Girls, Department of Orthopedic Surgery, Al-Azhar University, Cairo, Egypt.
Hassan Fathy El BehairyFaculty of Medicine for Girls, Al-zhraa University Hospital, Al-Azhar University, Cairo, Egypt.
Al-Azhar University · EGPrince Sattam Bin Abdulaziz University · SAKing Fahd Medical City · SAThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe knowledge about the effective implementation of corticosteroid injection (CS) with deep transverse friction massage (DTFM) and Mill's manipulation (MM) on clinical and radiological changes (Magnetic resonance imaging-MRI and Ultra sound) in lateral epicondylalgia (LE) is lacking. Therefore, the objective of this study is proposed to find and compare the effects of corticosteroid injection (CS) DTFM and Mill's manipulation on clinical and radiological changes in lateral epicondylalgia. DESIGN, SETTING,

participantsRandomized, single-blinded, controlled study was conducted on 60 LE participants at university hospital. The active MM group (n = 30) received corticosteroid injection with DTFM and active Mill's manipulation (MM) three sessions a week for 4 weeks and the sham MM group received corticosteroid injection with sham manipulation. The primary outcome was pain intensity, measured with the visual analog scale. The other outcome measures were percentage of injury measured by MRI and ultrasound, functional disability, handgrip strength, patient perception, kinesiophobia, depression status and quality of life which were measured at 4 weeks, 8weeks and at 6 months follow up.

resultsThe between-group difference in pain intensity at 4 weeks was 1.6 (CI 95% 0.97 to 2.22), which shows improvement in the active group than sham group. The similar effects have been noted after 8 weeks and at 6 months 2.0 (CI 95% 1.66 to 2.33) follow up in pain intensity. Similar improvements were also found on percentage of injury, functional disability, handgrip strength, patient perception, kinesiophobia, depression status and quality of life (p = 0.001).

conclusionCorticosteroid injection with DTFM and Mill's manipulation was superior to sham group for improving pain, percentage of injury, functional disability, handgrip strength, patient perception, kinesiophobia, depression status and quality of life in people with lateral epicondylalgia.

trial registrationClinical trial registration: CTRI/2020/05/025135 trial registered prospectively on 12/05/2020. https://trialsearch.who.int/Trial2.aspx?TrialID=CTRI/2020/05/025135.

Indexed as

Hand StrengthQuality of LifeAdrenal Cortex HormonesFrictionHumansMassageProspective StudiesTreatment OutcomeAdrenal Cortex Hormones

Identifiers

PMID36780557
PMCPMC9925075
OpenAlexW4320483442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.