Evidence map›Paper›PMID 36780127›Full record

SynthesisChild development

Language and reading impairments are associated with increased prevalence of non-right-handedness.

Filippo Abbondanza, Philip S Dale, Carol A Wang, Marianna E Hayiou-Thomas, Umar Toseeb, Tanner S Koomar, Karen G Wigg, Yu Feng, Kaitlyn M Price, Elizabeth N Kerr and 23 more

Erratum issuedOpen access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Handedness in schizophrenia and affective disorders: a large-scale cross-disorder study.European archives of psychiatry and clinical neuroscience · 2025
    Article
  6. Review
  7. Article
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  13. Review
  14. Animal models of developmental dyslexia.Frontiers in neuroscience · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors at 16 institutions in 6 countries.

Filippo AbbondanzaSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0002-1799-5492
Philip S DaleDepartment of Speech and Hearing Sciences, University of New Mexico, Albuquerque, New Mexico, USA.ORCID 0000-0002-7697-8510
Carol A WangSchool of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Marianna E Hayiou-ThomasDepartment of Psychology, University of York, York, UK.
Umar ToseebDepartment of Education, University of York, York, UK.ORCID 0000-0002-7536-2722
Tanner S KoomarDepartment of Psychiatry, The University of Iowa, Iowa City, Iowa, USA.
Karen G WiggDivision of Experimental and Translational Neuroscience, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Yu FengDivision of Experimental and Translational Neuroscience, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Kaitlyn M PriceDivision of Experimental and Translational Neuroscience, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Elizabeth N KerrDepartment of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
Sharon L GugerDepartment of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada.
Maureen W LovettProgram in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Lisa J StrugGenetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
Elsje van BergenDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-5860-5745
Conor V DolanDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
J Bruce TomblinDepartment of Psychiatry, The University of Iowa, Iowa City, Iowa, USA.
Kristina MollDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Ludwig-Maximilians-University Hospital Munich, Munchen, Germany.
Gerd Schulte-KörneDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Ludwig-Maximilians-University Hospital Munich, Munchen, Germany.
Nina NeuhoffDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Ludwig-Maximilians-University Hospital Munich, Munchen, Germany.
Andreas WarnkeJulius-Maximilians-University Würzburg, Würzburg, Germany.
Simon E FisherLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.
Cathy L BarrDivision of Experimental and Translational Neuroscience, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Jacob J MichaelsonDepartment of Psychiatry, The University of Iowa, Iowa City, Iowa, USA.
Dorret I BoomsmaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Margaret J SnowlingDepartment of Experimental Psychology, University of Oxford, Oxford, UK.ORCID 0000-0003-0836-3861
Charles HulmeDepartment of Education, University of Oxford, Oxford, UK.ORCID 0000-0001-7417-8926
Andrew J O WhitehouseTelethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.
Craig E PennellSchool of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
Dianne F NewburyDepartment of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK.
John SteinDepartment of Physiology, University of Oxford, Oxford, UK.
Joel B TalcottAston Brain Center, School of Life and Health Sciences, Aston University, Birmingham, UK.
Dorothy V M BishopDepartment of Experimental Psychology, University of Oxford, Oxford, UK.
Silvia ParacchiniSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0001-9934-8602
University Health Network · CAUniversity of Oxford · GBLudwig-Maximilians-Universität München · DEUniversity of Iowa · USUniversity of Toronto · CAVrije Universiteit Amsterdam · NLUniversity of Newcastle Australia · AUUniversity of St Andrews · GBUniversity of York · GBAston University · GBHospital for Sick Children · CAOxford Brookes University · GBRadboud University Nijmegen · NLThe Kids Research Institute Australia · AUUniversity of New Mexico · USUniversity of Würzburg · DE

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI EDWIN TED G. ABEL, Lane Strathearn · 2021 to 2026
$8.5M
Understanding the biology of language impairment through whole genome sequencingR01DC014489 · NIDCD · UNIVERSITY OF IOWA · PI MICHAELSON, JACOB JAMES · 2016 to 2020
$3.1M
Medical Research Council G0800523NICHD NIH HHS P50 HD103556NIDCD NIH HHS R01 DC014489Wellcome TrustWellcome Trust 217065/Z/19/Z
6 · The paper itself

Abstract

Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6-19 years old; European ethnicity) using a priori set criteria. A meta-analysis (N

Indexed as

Functional LateralityReadingAdolescentAdultBrainChildHumansLanguagePrevalenceYoung Adult

Identifiers

PMID36780127
PMCPMC10330064
OpenAlexW4320490383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.